Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brasil.
Maternidade Ana Braga, Manaus, Amazonas, Brasil.
Int J Gynaecol Obstet. 2021 Dec;155(3):524-531. doi: 10.1002/ijgo.13612. Epub 2021 Feb 22.
To compare the outcomes of adolescent versus adult women during pregnancy and puerperium admitted to a dedicated intensive care unit (ICU) in Manaus, Amazonas, Brazil.
In a retrospective cohort study, we retrieved data from the medical charts of 557 adolescent (<20 years) and adult (≥20 years) women. The association between demographic and clinical variables and the outcomes were compared in univariate and multivariate analyses.
The maternal severity index (MSI) of adult women was significantly higher than in adolescents. In univariate log-binomial regression analysis, pneumothorax and circulatory dysfunction were positively associated with the composite primary outcome of death or transfer (for more complex care), whereas eclampsia was negatively associated. Being an adolescent was not associated with this outcome, not even when adjusting for potential confounders. Conversely, being an adolescent was associated with fewer complications (secondary outcome) even after adjusting for potential confounders (type of admission, eclampsia, pre-eclampsia, surgical site infection, abdominal hemorrhage, drug abuse, metabolic syndrome, malnutrition, pneumothorax, or circulatory dysfunction).
In Manaus, Amazonas, Brazil, adult women admitted to the ICU because of gestational or birth complications had worse outcomes compared with adolescents.
比较巴西亚马孙州玛瑙斯市专门的重症监护病房(ICU)收治的妊娠和产褥期青少年与成年女性的结局。
本回顾性队列研究从玛瑙斯市 557 名青少年(<20 岁)和成年(≥20 岁)女性的病历中提取数据。在单变量和多变量分析中比较了人口统计学和临床变量与结局之间的关联。
成年女性的母体严重程度指数(MSI)明显高于青少年。在单变量二项式回归分析中,气胸和循环功能障碍与死亡或转院(更复杂的治疗)这一复合主要结局呈正相关,而子痫则呈负相关。即使调整了潜在混杂因素,青少年与该结局之间也没有关联。相反,即使在调整了潜在混杂因素(入院类型、子痫、先兆子痫、手术部位感染、腹部出血、药物滥用、代谢综合征、营养不良、气胸或循环功能障碍)后,青少年的并发症(次要结局)也更少。
在巴西亚马孙州玛瑙斯市,因妊娠或分娩并发症而入住 ICU 的成年女性的结局比青少年更差。