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一例罕见鼻窦血管外皮细胞瘤的临床及组织病理学表现

Clinical and histopathological findings of a rare sinonasal glomangiopericytoma.

作者信息

Moussaoui Zahraa Noureddine El, Najjar Zahraa Al, Diab Nada, Saker Zahraa, Choukr Hassane, Aoude Ahmad K, Saliba Marwan, Shoumar Bilal, Moussaoui Mohamad Reda Noureddine El

机构信息

Lebanese University, Faculty of Medical Sciences, Neurology Department, Beirut, Lebanon.

Al-Rassoul Al-Aazam Hospital, Pathology Department, Beirut, Lebanon.

出版信息

Autops Case Rep. 2023 Apr 10;13:e2023424. doi: 10.4322/acr.2023.424. eCollection 2023.

Abstract

Glomangiopericytoma is a rare vascular neoplasm of the nasal cavity and paranasal sinuses that occurs during the sixth or seventh decade of life. It is categorized as a borderline tumor with low malignant potential and classified as a distinct entity of sinonasal tumors with perivascular myoid phenotype by the World Health Organization (WHO). We report the case of a 50-year-old woman with nasal obstruction and severe epistaxis. The nasal sinuses computed tomography (CT), and magnetic resonance imaging (MRI) demonstrated a 3.1 cm soft tissue mass occupying the upper part of the left nasal cavity invading the left paranasal sinuses and nasal septum, and the left eye medial rectus muscle. A total mass resection was performed by nasal endoscopy. The histological and immunohistochemical examination yielded the diagnosis of glomangiopericytoma. This case report aims to contribute to the knowledge of nasal neoplasms. The need for more data on this entity is the main obstacle to developing standardized treatment guidelines.

摘要

血管外皮细胞瘤是鼻腔和鼻窦罕见的血管性肿瘤,多发生于60或70岁。它被归类为具有低恶性潜能的交界性肿瘤,并被世界卫生组织(WHO)列为具有血管周围肌样表型的鼻窦肿瘤的一个独特类型。我们报告一例50岁女性,有鼻塞和严重鼻出血症状。鼻窦计算机断层扫描(CT)和磁共振成像(MRI)显示一个3.1厘米的软组织肿块,占据左侧鼻腔上部,侵犯左侧鼻窦和鼻中隔以及左眼内直肌。通过鼻内镜进行了肿物全切术。组织学和免疫组化检查确诊为血管外皮细胞瘤。本病例报告旨在增进对鼻腔肿瘤的认识。关于该肿瘤实体缺乏更多数据是制定标准化治疗指南的主要障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c02/10124557/44b908b6cbad/autopsy-13-e2023424-g01.jpg

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