Institute of Internal Medicine and Geriatrics, Università Cattolica del Sacro Cuore, Rome, Italy; Applied Kinesiology Laboratory-LCA, School of Physical Education, University of Campinas, Campinas, SP, Brazil.
Applied Kinesiology Laboratory-LCA, School of Physical Education, University of Campinas, Campinas, SP, Brazil.
Exp Gerontol. 2021 Apr;146:111245. doi: 10.1016/j.exger.2021.111245. Epub 2021 Jan 19.
The present study investigated whether hypertension, blood pressure, and antihypertensive therapy were associated with frailty status in community-dwelling older adults. In addition, we tested whether such associations were consistent across different frailty instruments.
Two-hundred older adults were enrolled in the study. Participant frailty status was determined according to a modified physical frailty phenotype (mFP), the FRAIL scale, and the Study of Osteoporotic Fracture (SOF) index. Blood pressure was assessed three times, in three different days, and mean values were used in the final analysis. Information pertaining to disease conditions and antihypertensive therapy were collected by two researchers through self-report and careful review of medical charts.
No significant differences in hemodynamic parameters, hypertension diagnosis, and antihypertensive therapy were observed across frailty statuses, regardless of the frailty assessment tool used.
Findings of the present study indicate that hypertension, blood pressure levels and antihypertensive medication were not cross-sectionally associated with frailty status in cognitively preserved community-dwelling older adults with low prevalence of comorbidities, regardless of the tool used for frailty identification.
本研究旨在探讨高血压、血压和降压治疗与社区居住的老年人虚弱状态之间的关系。此外，我们还测试了这些关联是否在不同的虚弱工具之间一致。
共有 200 名老年人参加了这项研究。根据改良的身体虚弱表型 (mFP)、脆弱性量表 (FRAIL) 和骨质疏松性骨折研究 (SOF) 指数来确定参与者的虚弱状态。血压在三个不同的日子里测量了三次，最终分析采用平均值。通过两名研究人员通过自我报告和仔细审查医疗记录收集与疾病状况和降压治疗相关的信息。
无论使用哪种虚弱评估工具，在虚弱状态方面，血流动力学参数、高血压诊断和降压治疗均无显著差异。
本研究的结果表明，在认知功能正常且合并症患病率较低的社区居住的老年人中，无论使用哪种虚弱识别工具，高血压、血压水平和降压药物与虚弱状态均无横断面关联。
