The University of Sydney Central Clinical School, The Faculty of Medicine and Health, The University of Sydney, 92-95 Parramatta Road, Camperdown, New South Wales 2050, Australia; The Woolcock Institute of Medical Research, Apartment 203, Building 2G, Van Phuc Diplomatic Compound 298 Kim Ma Street Ba Dinh District, Hanoi, Vietnam.
Department of Public Health, Institute for Tropical Medicine, Kronenburgstraat 43, 2000 Antwerp, Belgium.
J Clin Epidemiol. 2021 May;133:101-110. doi: 10.1016/j.jclinepi.2021.01.007. Epub 2021 Jan 19.
Stigma contributes to diagnostic delay, disease concealment, and reduced wellbeing for people with multidrug-resistant tuberculosis (MDR-TB) and their communities. Despite the negative effects of stigma, there are no scales to measure stigma in people with MDR-TB. This study aimed to develop and validate a scale to measure stigma in people affected by MDR-TB in Vietnam.
People with rifampicin-resistant (RR)-MDR-TB who had completed at least 3 months of treatment were invited to complete a survey containing 45 draft stigma items. Data analysis included exploratory factor analysis, internal consistency, content, criterion and construct validity, and test-retest reliability.
A total of 315 people with RR/MDR-TB completed the survey. Exploratory factor analysis revealed a 14 item RR/MDR-TB stigma scale with four subscales, including guilt, social exclusion, physical isolation, and blame. Internal consistency and test-retest reliability were good (Cronbach's Alpha = 0.76, ICC = 0.92). Construct validity was adequate with moderate correlations with related constructs.
Our RR/MDR-TB Scale demonstrated good psychometric properties in Vietnam. This scale will assist in the measurement of stigma in people with RR/MDR-TB. It will also aid in the evaluation of stigma reduction interventions in people with RR/MDR-TB.
污名化会导致耐多药结核病（MDR-TB）患者及其所在社区的诊断延误、疾病隐瞒和幸福感降低。尽管污名化有负面影响，但目前还没有专门用于衡量 MDR-TB 患者污名化的量表。本研究旨在开发和验证一种用于衡量越南 MDR-TB 患者污名化的量表。
已完成至少 3 个月 RR-MDR-TB 治疗的 RR-MDR-TB 患者受邀完成一项包含 45 个草案污名项目的调查。数据分析包括探索性因素分析、内部一致性、内容、标准和结构有效性以及测试-重测信度。
共有 315 名 RR/MDR-TB 患者完成了调查。探索性因素分析显示，RR/MDR-TB 污名量表有 14 个项目，分为四个亚量表，包括内疚、社会排斥、身体隔离和指责。内部一致性和测试-重测信度良好（Cronbach's Alpha = 0.76，ICC = 0.92）。结构有效性适度，与相关结构呈中度相关。
我们的 RR/MDR-TB 量表在越南具有良好的心理测量学特性。该量表将有助于衡量 RR/MDR-TB 患者的污名化。它还将有助于评估 RR/MDR-TB 患者减少污名化干预的效果。
