Suppr超能文献

伴有腹膜炎的大量非伤寒沙门氏菌脾脓肿非创伤性破裂:病例报告及文献复习

Non-traumatic rupture of voluminous non-typhoid Salmonella splenic abscess presenting with peritonitis: Case report and review of the literature.

作者信息

Evola Giuseppe, Piazzese Enrico, Cantella Roberto, Iudica Marianna, Veroux Gastone, Sarvà Salvatore

机构信息

General and Emergency Surgery Department, Garibaldi Hospital, Piazza Santa Maria di Gesù 5, 95100, Catania, Italy.

General and Emergency Surgery Department, Garibaldi Hospital, Piazza Santa Maria di Gesù 5, 95100, Catania, Italy.

出版信息

Int J Surg Case Rep. 2021 Feb;79:160-163. doi: 10.1016/j.ijscr.2020.12.081. Epub 2021 Jan 15.

Abstract

INTRODUCTION AND IMPORTANCE

Splenic abscess (SA) is an uncommon, life-threatening disease with about 600 reported cases in the literature. It is caused by various infective pathogens and generally occurs in immunocompromised patients. SA is a rare complication of non-typhoid Salmonella (NTS) infection. Diagnosis of ruptured SA is a challenge because the absence of specific symptoms and signs. Abdominal computed tomography (CT) scan represents the gold standard in diagnosing of SA. Splenectomy is the treatment of choice of ruptured SA with peritonitis.

CASE PRESENTATION

A 26-year-old Caucasian female was admitted to the Emergency Department with a three-day history of abdominal pain and fever. Physical examination revealed severe and generalized abdominal pain on superficial and deep palpation with obvious muscle guarding and rebound tenderness. Abdominal CT scan showed ruptured SA. Laboratory tests reported anemia (hemoglobin 10.4 g/dl). The patient was taken emergently to the operating room for splenectomy. The postoperative course was uneventful, the patient was discharged on the 7th post-operative day. Diagnosis of NTS SA was made by pus cultures.

CLINICAL DISCUSSION

SA is a rare complication of NTS infection associated with high morbidity and mortality rates. Although different types of treatment of SA are reported in the literature, splenectomy represents the treatment of choice of ruptured SA.

CONCLUSION

NTS SA is difficult to diagnose because of its rarity and non-specific clinical presentation, often fatal if left untreated. Although there is no gold standard for treating SA, splenectomy with peritoneal lavage is mandatory in case of ruptured SA with peritonitis.

摘要

引言与重要性

脾脓肿(SA)是一种罕见的、危及生命的疾病,文献报道约有600例。它由多种感染性病原体引起,通常发生在免疫功能低下的患者中。SA是非伤寒沙门氏菌(NTS)感染的罕见并发症。破裂性SA的诊断具有挑战性,因为缺乏特异性症状和体征。腹部计算机断层扫描(CT)是诊断SA的金标准。脾切除术是治疗伴有腹膜炎的破裂性SA的首选方法。

病例介绍

一名26岁的白种女性因腹痛和发热三天入院急诊科。体格检查发现,浅部和深部触诊时均有严重的全腹疼痛,伴有明显的肌紧张和反跳痛。腹部CT扫描显示脾脓肿破裂。实验室检查报告有贫血(血红蛋白10.4g/dl)。患者紧急被送往手术室进行脾切除术。术后过程顺利,患者于术后第7天出院。通过脓液培养确诊为NTS脾脓肿感染。

临床讨论

SA是NTS感染的罕见并发症,发病率和死亡率都很高。尽管文献报道了SA的不同治疗方法,但脾切除术是破裂性SA的首选治疗方法。

结论

由于NTS脾脓肿感染罕见且临床表现不具特异性,因此难以诊断,如果不治疗往往会致命。虽然治疗SA没有金标准,但对于伴有腹膜炎的破裂性SA,必须进行脾切除并腹腔灌洗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4f0/7815976/f42be9ac5091/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验