Bhasin S, Sartoris D J, Fellingham L, Zlatkin M B, Andre M, Resnick D
Department of Radiology, University of California Medical Center, San Diego 92103.
Radiology. 1988 Apr;167(1):145-9. doi: 10.1148/radiology.167.1.3347716.
Dual-photon absorptiometry (DPA) of the proximal femur cannot independently measure cortical and high-turnover cancellous bone. In this investigation, integrated cancellous, cortical, and total bone densities in the femoral neck and intertrochanteric region were measured bilaterally in 22 women aged 42-75 years. Contiguous section data were analyzed with two different protocols by means of three-dimensional histogram software. Single-section quantitative computed tomography (CT) was used to determine mean mineral equivalent values for vertebral cancellous bone from T-11 to L-3 in each woman. Significant correlation was found between cancellous bone density at the two sites, as well as between total femoral and vertebral measurements. Femoral cortical bone density was predicted less well by means of the vertebral cancellous data. Cortical, cancellous, and total proximal femoral density values tended to exhibit bilateral symmetry. Quantitative three-dimensional volumetric CT affords comprehensive evaluation of proximal femoral mineral status because of its capability for selective measurement of cortical, cancellous, and total bone density.
近端股骨的双能光子吸收测定法（DPA）无法独立测量皮质骨和高转换松质骨。在本研究中，对22名年龄在42至75岁的女性双侧测量了股骨颈和转子间区域的松质骨、皮质骨及总骨密度。通过三维直方图软件，采用两种不同方案分析连续断层数据。使用单断层定量计算机断层扫描（CT）测定每位女性T-11至L-3椎体松质骨的平均矿物质等效值。发现两个部位的松质骨密度之间以及股骨和椎体测量值之间存在显著相关性。通过椎体松质骨数据对股骨皮质骨密度的预测效果较差。股骨近端皮质骨、松质骨和总骨密度值往往呈现双侧对称性。定量三维容积CT能够选择性测量皮质骨、松质骨和总骨密度，因此可对近端股骨矿物质状态进行全面评估。
