Sartoris D J, André M, Resnik C S, Resnick D
Radiology. 1986 Sep;160(3):707-12. doi: 10.1148/radiology.160.3.3755536.
A new technique has been developed for quantitative assessment of trabecular bone content in the proximal femur using computed tomography (CT). The method employs the same contoured calibration phantom currently used for vertebral mineral studies and can be performed on any standard body scanner. Both femurs are evaluated simultaneously, and an integral approach to mean density determinations compensates for the complex geometry and trabecular architecture of the region. Specimen studies have documented acceptable reproducibility, and radiation dose and examination time are comparable to those of quantitative CT in the spine. Greater inherent accuracy has been achieved more rapidly through the addition of three-dimensional histogram analysis using a free-standing CT data processor. High correlation with vertebral trabecular bone content has been documented in the limited number of patients studied to date. Widespread availability of the technique and the high frequency of fractures related to metabolic bone disease in the proximal femur render the method a potentially valuable contribution to noninvasive bone densitometry.
一种利用计算机断层扫描（CT）对股骨近端小梁骨含量进行定量评估的新技术已经开发出来。该方法采用了目前用于椎体矿物质研究的相同轮廓校准体模，并且可以在任何标准的全身扫描仪上进行。双侧股骨同时进行评估，采用积分法测定平均密度可补偿该区域复杂的几何形状和小梁结构。标本研究已证明其具有可接受的重复性，并且辐射剂量和检查时间与脊柱定量CT相当。通过使用独立的CT数据处理器进行三维直方图分析，能更快地实现更高的固有准确性。在迄今为止研究的有限数量患者中，已证明该技术与椎体小梁骨含量具有高度相关性。该技术的广泛可用性以及股骨近端与代谢性骨病相关的骨折高发性，使得该方法对无创骨密度测定具有潜在的重要贡献。
