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[F]FDG PET/CT在侵袭性真菌感染管理中的附加价值

The Added Value of [F]FDG PET/CT in the Management of Invasive Fungal Infections.

作者信息

Ankrah Alfred O, Creemers-Schild Dina, de Keizer Bart, Klein Hans C, Dierckx Rudi A J O, Kwee Thomas C, Span Lambert F R, de Jong Pim A, Sathekge Mike M, Glaudemans Andor W J M

机构信息

Medical Imaging Center, University of Groningen, University Medical Center Groningen, 9700 AC Groningen, The Netherlands.

Department of Nuclear Medicine, University of Pretoria, Steve Biko Academic Hospital, Pretoria 0001, South Africa.

出版信息

Diagnostics (Basel). 2021 Jan 17;11(1):137. doi: 10.3390/diagnostics11010137.

DOI:10.3390/diagnostics11010137
PMID:33477267
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7830875/
Abstract

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [F]FDG PET/CT for 94.4% of the scans performed. [F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [F]FDG PET/CT added value in the management of the IFIs.

摘要

基于解剖结构的成像方法是评估侵袭性真菌感染（IFI）时常用的成像方法。[F]FDG PET/CT也已用于IFI的评估。我们评估了在评估IFI时，将[F]FDG PET/CT添加到最常用的基于解剖结构的研究中所带来的附加价值。该研究在荷兰的两家大学医学中心进行。检索了在[F]FDG PET/CT扫描后两周内进行的[F]FDG PET/CT和基于解剖结构的成像报告，并记录了每个检查中IFI病变的存在情况和部位。我们纳入了73例患者进行的155次[F]FDG PET/CT扫描。共研究了216项基于解剖结构的检查，包括80次胸部X光、89次计算机断层扫描、14次磁共振成像检查和33次超声成像检查。在94.4%的扫描中，基于解剖结构的检查结果与[F]FDG PET/CT结果一致。在48.6%的扫描中，[F]FDG PET/CT检测到了基于解剖结构的检查所成像区域之外的IFI病变。在74%的患者中，[F]FDG PET/CT在IFI的管理中具有附加价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/0fc5baa93350/diagnostics-11-00137-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/954b375fdce8/diagnostics-11-00137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/469ba68ee833/diagnostics-11-00137-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/c770795722fb/diagnostics-11-00137-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/0fc5baa93350/diagnostics-11-00137-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/954b375fdce8/diagnostics-11-00137-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/469ba68ee833/diagnostics-11-00137-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/c770795722fb/diagnostics-11-00137-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e614/7830875/0fc5baa93350/diagnostics-11-00137-g004.jpg

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