脂质是否可能成为自杀行为的标志物？
Are Lipids Possible Markers of Suicide Behaviors?
作者信息
Kułak-Bejda Agnieszka, Bejda Grzegorz, Lech Magdalena, Waszkiewicz Napoleon
机构信息
Department of Psychiatry, Medical University of Bialystok, 16-070 Choroszcz, Poland.
Faculty of General Medicine, School of Medical Science in Bialystok, 15-875 Bialystok, Poland.
出版信息
J Clin Med. 2021 Jan 18;10(2):333. doi: 10.3390/jcm10020333.
Abstract
Suicides and suicidal behaviors are very important causes of mortality and morbidity and have become a serious global problem. More than 800,000 people die from suicide every year. Previous researches have established that lipids play an important role in the pathogenesis of suicide. Moreover, lipid levels might be a biological marker of suicide. A lot of researchers have tried to identify biological markers that might be related to depressive disorder, bipolar disorder or schizophrenia and suicidal behavior. It was also important to consider the usefulness of an additional tool for prevention actions. Metabolic deregulation, particularly low total cholesterol and low-density lipoproteins-cholesterol levels may cause higher suicide risk in patients with these psychiatric disorders.
摘要
自杀及自杀行为是导致死亡和发病的非常重要的原因，已成为一个严重的全球性问题。每年有超过80万人死于自杀。先前的研究已证实脂质在自杀的发病机制中起重要作用。此外，血脂水平可能是自杀的一个生物学标志物。许多研究人员试图找出可能与抑郁症、双相情感障碍或精神分裂症及自杀行为相关的生物学标志物。考虑到一种额外预防工具的实用性也很重要。代谢失调，尤其是总胆固醇和低密度脂蛋白胆固醇水平低，可能会使患有这些精神疾病的患者自杀风险更高。
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