Unit of General Surgery 2, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy.
Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
Medicina (Kaunas). 2021 Jan 19;57(1):80. doi: 10.3390/medicina57010080.
There is general agreement on the benefits of laparoscopy for treatment of rectal and left colon cancers, whereas findings regarding the comparison of laparoscopic and open right colonic resections are discordant. The aim of this systematic review and meta-analysis was to assess the outcomes and advantages of laparoscopic versus transverse-incision open surgery for management of right colon cancer. A systematic review was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Comparative studies evaluating the results of laparoscopic and transverse-incision open right hemicolectomies were analyzed. The measured outcomes were mean operative time, time to feeding, duration of hospital stay, and number of lymph nodes harvested. A total of 5 studies including 318 patients met the inclusion criteria. Meta-analysis revealed no differences in time to resume oral feeding, hospital stay, and number of lymph nodes harvested in between groups, but mean length of surgery was significantly longer in the laparoscopic group. These data confirm that the preferred approach to right hemicolectomy is yet unclear. Laparoscopy has a longer operative time than transverse-incision open surgery, and no significant short-term benefits were observed for the studied parameters. Well-designed randomized control trials (RCTs) might help to identify the differences between these two techniques for the surgical treatment of right colon cancer.
对于直肠和左结肠癌的治疗,腹腔镜具有公认的优势,而腹腔镜与开腹右半结肠切除术的比较结果则存在争议。本系统评价和荟萃分析的目的是评估腹腔镜与经腹直肌切口开腹手术治疗右半结肠癌的结局和优势。本研究按照系统评价和荟萃分析的首选报告项目(PRISMA)指南进行系统评价。分析了评估腹腔镜与经腹直肌切口开腹右半结肠切除术结果的比较研究。测量的结果是手术的平均时间、恢复进食的时间、住院时间和淋巴结清扫的数量。共有 5 项研究,包括 318 例患者符合纳入标准。荟萃分析显示,两组之间在恢复口服进食时间、住院时间和淋巴结清扫数量方面没有差异,但腹腔镜组的手术时间明显更长。这些数据证实,右半结肠切除术的首选方法尚不清楚。腹腔镜手术的手术时间比经腹直肌切口开腹手术长,且在研究的参数方面没有观察到明显的短期获益。精心设计的随机对照试验(RCT)可能有助于确定这两种技术在右半结肠癌手术治疗中的差异。