Department of Clinical Biochemistry, Bispebjerg, Frederiksberg University Hospital, Copenhagen, Denmark.
Motryx Inc., Halifax, Canada.
Ann Clin Biochem. 2021 Jul;58(4):280-288. doi: 10.1177/0004563221992822. Epub 2021 Feb 15.
The most common way to validate a pneumatic tube system is to compare pneumatic tube system-transported blood samples to blood samples carried by hand. The importance of measuring the forces inside the pneumatic tube system has also been emphasized. The aim of this study was to define a validation protocol using a mini data logger (VitalVial, Motryx Inc., Canada) to reduce the need for donor samples in pneumatic tube system validation.
As an indicator of the total vibration, the blood samples are exposed to under pneumatic tube system transportation; the area under the curve was determined by a VitalVial for all hospital Tempus600 lines using a five-day validation protocol. Only the three lines with the highest area under the curves were clinically validated by analysing potassium, lactate dehydrogenase and aspartate aminotransferase. A month after pneumatic tube system commissioning, a follow-up on laboratory data was performed.
Mean area under the curve of the six lines ranged between 347 and 581. The variability of the area under the curve was between 1.51 and 11.55%. In the laboratory data follow-up, an increase in lactate dehydrogenase haemolysis was seen from the three lines with the highest area under the curve and the emergency department, which was not detected in the clinical validation. When the Tempus600 system was in commission, a higher mean area under the curve was measured.
A three-day validation protocol using VitalVials is enough to determine the stability of a Tempus600 system and can greatly reduce the need for donor samples. When in commission, the stability of the pneumatic tube system should be verified and lactate dehydrogenase haemolysis should be routinely checked.
验证气动输送系统最常用的方法是比较气动输送系统输送的血样和人工携带的血样。测量气动输送系统内的力的重要性也得到了强调。本研究的目的是使用微型数据记录仪（VitalVial，Motryx Inc.，加拿大）定义一个验证方案，以减少气动输送系统验证中对供体样本的需求。
作为气动输送系统运输下血液样本总振动的指标，使用 VitalVial 对所有医院 Tempus600 线路进行了为期五天的验证方案，确定所有线路的曲线下面积。只有三条曲线下面积最高的线路通过分析钾、乳酸脱氢酶和天冬氨酸转氨酶进行了临床验证。在气动输送系统投入使用一个月后，对实验室数据进行了随访。
六条线路的平均曲线下面积在 347 到 581 之间。曲线下面积的变异性在 1.51 到 11.55%之间。在实验室数据随访中，从三条曲线下面积最高的线路和急诊部观察到乳酸脱氢酶溶血增加，而在临床验证中未检测到。当 Tempus600 系统投入使用时，测量到更高的平均曲线下面积。
使用 VitalVials 进行三天验证方案足以确定 Tempus600 系统的稳定性，并大大减少对供体样本的需求。当系统投入使用时，应验证气动输送系统的稳定性，并定期检查乳酸脱氢酶溶血。
