Medical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.
Maternal and Children Metabolic-Genetic Key Laboratory, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.
J Int Med Res. 2021 Jan;49(1):300060520986668. doi: 10.1177/0300060520986668.
Congenital ventricular diverticulum is a rare abnormality that may occur as an isolated malformation. Most cases are accompanied by pericardial effusion. Prenatal counseling can be difficult because the prognosis is uncertain and there is no consensus approach to prenatal management. We describe a case of congenital cardiac diverticulum complicated by large pericardial effusion in one of monochorionic diamniotic twins. The case was diagnosed by ultrasonography at 21 weeks of gestation. Therapeutic pericardiocentesis at 22 weeks resulted in complete resolution of the effusion and led to a favorable fetal outcome. We summarize the interventions and pregnancy outcomes in cases of cardiac diverticula reported in the literature.
Better awareness of clinical features, in utero therapies, and pregnancy outcomes could help define and improve prenatal management of congenital ventricular diverticula.
先天性心室憩室是一种罕见的异常，可能作为一种孤立的畸形发生。大多数病例伴有心包积液。由于预后不确定，也没有共识的产前管理方法，因此产前咨询可能很困难。我们描述了一例单绒毛膜双羊膜囊双胎之一合并大量心包积液的先天性心脏憩室病例。该病例在妊娠 21 周时通过超声检查诊断。22 周时进行的治疗性心包穿刺术导致积液完全消退，并导致胎儿结局良好。我们总结了文献中报道的心脏憩室病例的干预措施和妊娠结局。
更好地了解临床特征、宫内治疗和妊娠结局可以帮助确定和改善先天性心室憩室的产前管理。
