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经直肠超声引导前列腺活检后并发感染性动脉瘤和椎间盘炎的前列腺脓肿:病例报告及文献复习。

Prostatic abscess with infected aneurysms and spondylodiscitis after transrectal ultrasound-guided prostate biopsy: a case report and literature review.

机构信息

Department of Urology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.

出版信息

BMC Urol. 2021 Jan 21;21(1):11. doi: 10.1186/s12894-021-00780-0.

DOI:10.1186/s12894-021-00780-0
PMID:33478455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7818722/
Abstract

BACKGROUND

Transrectal ultrasonography (TRUS)-guided prostate biopsy is the conventional method of diagnosing prostate cancer. TRUS-guided prostate biopsy can occasionally be associated with severe complications. Here, we report the first case of a prostate abscess with aneurysms and spondylodiscitis as a complication of TRUS-guided prostate biopsy, and we review the relevant literature.

CASE PRESENTATION

A 78-year-old man presented with back pain, sepsis, and prostate abscesses. Twenty days after TRUS-guided prostate biopsy, he was found to have a 20-mm diameter abdominal aortic aneurysm that expanded to 28.2 mm in the space of a week, despite antibiotic therapy. Therefore, he underwent transurethral resection of the prostate to control prostatic abscesses. Although his aneurysm decreased to 23 mm in size after surgery, he continued to experience back pain. He was diagnosed as having pyogenic spondylitis and this was managed using a lumbar corset. Sixty-four days after the prostate biopsy, the aneurysm had re-expanded to 30 mm; therefore, we performed endovascular aneurysm repair (EVAR) using a microcore stent graft 82 days after the biopsy. Four days after the EVAR, the patient developed acute cholecystitis, and he underwent endoscopic retrograde biliary drainage. One hundred and sixty days after the prostate biopsy, all the complications had improved, and he was discharged. A literature review identified a further six cases of spondylodiscitis that had occurred after transrectal ultrasound-guided prostate biopsy.

CONCLUSIONS

We have reported the first case of a complication of TRUS-guided prostate biopsy that involved prostatic abscesses, aneurysms, and spondylodiscitis. Although such complications are uncommon, clinicians should be aware of the potential for such severe complications of this procedure to develop.

摘要

背景

经直肠超声(TRUS)引导下前列腺活检是诊断前列腺癌的常规方法。TRUS 引导下前列腺活检偶尔会伴有严重并发症。在此,我们报告首例 TRUS 引导下前列腺活检后并发前列腺脓肿、动脉瘤和脊椎炎的病例,并复习相关文献。

病例介绍

一名 78 岁男性因背痛、脓毒症和前列腺脓肿就诊。在 TRUS 引导下前列腺活检后 20 天,发现其腹主动脉瘤直径 20mm,一周内扩大至 28.2mm,尽管给予抗生素治疗。因此,他接受了经尿道前列腺切除术以控制前列腺脓肿。尽管手术后他的动脉瘤缩小至 23mm,但仍持续背痛。他被诊断为化脓性脊椎炎,使用腰部支具进行治疗。前列腺活检后 64 天,动脉瘤再次扩大至 30mm,因此在活检后 82 天行血管内动脉瘤修复术(EVAR)。EVAR 后 4 天,患者发生急性胆囊炎,行内镜逆行胆胰管引流术。前列腺活检后 160 天,所有并发症均改善,患者出院。文献复习发现另外 6 例经直肠超声引导前列腺活检后发生脊椎炎的病例。

结论

我们报告首例 TRUS 引导下前列腺活检后并发前列腺脓肿、动脉瘤和脊椎炎的病例。虽然这种并发症并不常见,但临床医生应该意识到这种手术可能会出现严重并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/c6adac521a2f/12894_2021_780_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/995e74233dba/12894_2021_780_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/8e182b79d1c2/12894_2021_780_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/c6adac521a2f/12894_2021_780_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/995e74233dba/12894_2021_780_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/8e182b79d1c2/12894_2021_780_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f584/7818722/c6adac521a2f/12894_2021_780_Fig3_HTML.jpg

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本文引用的文献

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Ann Vasc Surg. 2019 Nov;61:469.e1-469.e4. doi: 10.1016/j.avsg.2019.05.021. Epub 2019 Aug 2.
2
Spondylodiscitis with Epidural and Psoas Muscle Abscesses as Complications After Transrectal Ultrasound-guided Prostate Biopsy: Report of a Rare Case.经直肠超声引导下前列腺活检后并发脊柱炎、硬膜外脓肿和腰大肌脓肿:1例罕见病例报告
Eur J Case Rep Intern Med. 2017 Aug 2;4(8):000694. doi: 10.12890/2017_000694. eCollection 2017.
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A case of infective endocarditis and pyogenic spondylitis after transrectal ultrasound guided prostate biopsy.
前列腺脓肿合并耐多药革兰阴性杆菌脾脓肿 1 例报告并文献复习
Am J Mens Health. 2022 Jul-Aug;16(4):15579883221108898. doi: 10.1177/15579883221108898.
经直肠超声引导下前列腺活检后发生感染性心内膜炎和化脓性脊柱炎1例。
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Epidural abscess with associated spondylodiscitis following prostatic biopsy.前列腺活检后并发脊椎骨髓炎的硬膜外脓肿。
Ann R Coll Surg Engl. 2015 Jul;97(5):e81-2. doi: 10.1308/003588415X14181254790563.
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Sepsis and 'superbugs': should we favour the transperineal over the transrectal approach for prostate biopsy?脓毒症和“超级细菌”:我们应该赞成经会阴途径而非经直肠途径进行前列腺活检吗?
BJU Int. 2014 Sep;114(3):384-8. doi: 10.1111/bju.12536. Epub 2014 Feb 19.
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