Department of Urology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
BMC Urol. 2021 Jan 21;21(1):11. doi: 10.1186/s12894-021-00780-0.
Transrectal ultrasonography (TRUS)-guided prostate biopsy is the conventional method of diagnosing prostate cancer. TRUS-guided prostate biopsy can occasionally be associated with severe complications. Here, we report the first case of a prostate abscess with aneurysms and spondylodiscitis as a complication of TRUS-guided prostate biopsy, and we review the relevant literature.
A 78-year-old man presented with back pain, sepsis, and prostate abscesses. Twenty days after TRUS-guided prostate biopsy, he was found to have a 20-mm diameter abdominal aortic aneurysm that expanded to 28.2 mm in the space of a week, despite antibiotic therapy. Therefore, he underwent transurethral resection of the prostate to control prostatic abscesses. Although his aneurysm decreased to 23 mm in size after surgery, he continued to experience back pain. He was diagnosed as having pyogenic spondylitis and this was managed using a lumbar corset. Sixty-four days after the prostate biopsy, the aneurysm had re-expanded to 30 mm; therefore, we performed endovascular aneurysm repair (EVAR) using a microcore stent graft 82 days after the biopsy. Four days after the EVAR, the patient developed acute cholecystitis, and he underwent endoscopic retrograde biliary drainage. One hundred and sixty days after the prostate biopsy, all the complications had improved, and he was discharged. A literature review identified a further six cases of spondylodiscitis that had occurred after transrectal ultrasound-guided prostate biopsy.
We have reported the first case of a complication of TRUS-guided prostate biopsy that involved prostatic abscesses, aneurysms, and spondylodiscitis. Although such complications are uncommon, clinicians should be aware of the potential for such severe complications of this procedure to develop.
经直肠超声(TRUS)引导下前列腺活检是诊断前列腺癌的常规方法。TRUS 引导下前列腺活检偶尔会伴有严重并发症。在此,我们报告首例 TRUS 引导下前列腺活检后并发前列腺脓肿、动脉瘤和脊椎炎的病例,并复习相关文献。
一名 78 岁男性因背痛、脓毒症和前列腺脓肿就诊。在 TRUS 引导下前列腺活检后 20 天,发现其腹主动脉瘤直径 20mm,一周内扩大至 28.2mm,尽管给予抗生素治疗。因此,他接受了经尿道前列腺切除术以控制前列腺脓肿。尽管手术后他的动脉瘤缩小至 23mm,但仍持续背痛。他被诊断为化脓性脊椎炎,使用腰部支具进行治疗。前列腺活检后 64 天,动脉瘤再次扩大至 30mm,因此在活检后 82 天行血管内动脉瘤修复术(EVAR)。EVAR 后 4 天,患者发生急性胆囊炎,行内镜逆行胆胰管引流术。前列腺活检后 160 天,所有并发症均改善,患者出院。文献复习发现另外 6 例经直肠超声引导前列腺活检后发生脊椎炎的病例。
我们报告首例 TRUS 引导下前列腺活检后并发前列腺脓肿、动脉瘤和脊椎炎的病例。虽然这种并发症并不常见,但临床医生应该意识到这种手术可能会出现严重并发症。