Pakhale Smita, Tariq Saania, Huynh Nina, Jama Sadia, Kaur Tina, Charron Catherine, Florence Kelly, Nur Fozia, Bustamante-Bawagan Margaret Ella, Bignell Ted, Boyd Robert, Haddad Joanne, Kendzerska Tetyana, Alvarez Gonzalo
Department of Medicine, The Ottawa Hospital, 501 Smyth Road, Ottawa, Ontario, K1H 8L6, Canada.
The Ottawa Hospital Research Institute (OHRI), Ottawa, Canada.
BMC Public Health. 2021 Jan 21;21(1):183. doi: 10.1186/s12889-021-10209-w.
Globally the burden of Obstructive Lung Diseases (OLD) is growing, however its effect on urban poor populations with the high prevalence of tobacco dependence is virtually unknown. The purpose of this project is to estimate the prevalence and burden of OLD in the urban, low-income populations of Ottawa, Canada.
The study presented in this paper was part of the PROMPT (Management and Point-of-Care for Tobacco Dependence) project; a prospective cohort study in a community-based setting (n = 80) with meaningful Patient Engagement from design to dissemination. Spirometry data, standardized questionnaires and semi-structured interviews from PROMPT were interpreted to understand the lung function, disease burden and social determinants (respectively) in this population.
The prevalence of OLD among those who completed spirometry (N = 64) was 45-59%. Generic and disease-specific quality of life was generally poor in all PROMPT participants, even those without OLD, highlighting the higher disease burden this vulnerable population faces. Quality of life was impacted by two major themes, including i) socioeconomic status and stress and ii) social networks and related experiences of trauma.
The prevalence and disease burden of OLD is significantly higher in Ottawa's urban poor population than what is observed in the general Canadian population who smoke, suggesting an etiological role of the social determinants of health. This urges the need for comprehensive care programs addressing up-stream factors leading to OLDs, including poor access and utilization of preventive healthcare addressing the social determinants of health.
ClinicalTrails.gov - NCT03626064 , Retrospective registered: August 2018.
在全球范围内,阻塞性肺病(OLD)的负担正在增加,然而其对烟草依赖高发的城市贫困人口的影响几乎未知。本项目的目的是估计加拿大渥太华城市低收入人群中OLD的患病率和负担。
本文介绍的研究是PROMPT(烟草依赖管理与即时护理)项目的一部分;这是一项在社区环境中进行的前瞻性队列研究(n = 80),从设计到传播都有有意义的患者参与。对PROMPT的肺活量测定数据、标准化问卷和半结构化访谈进行解读,以了解该人群的肺功能、疾病负担和社会决定因素(分别)。
完成肺活量测定的人群(N = 64)中OLD的患病率为45%-59%。在所有PROMPT参与者中,一般和特定疾病的生活质量普遍较差,即使是那些没有OLD的参与者,这突出了这一弱势群体面临的更高疾病负担。生活质量受到两个主要主题的影响,包括:i)社会经济地位和压力,以及ii)社会网络和相关创伤经历。
渥太华城市贫困人口中OLD的患病率和疾病负担明显高于加拿大吸烟人群的总体观察结果,这表明健康的社会决定因素具有病因学作用。这就迫切需要制定综合护理计划,解决导致OLD的上游因素,包括获得和利用针对健康社会决定因素的预防性医疗服务不足的问题。
ClinicalTrails.gov - NCT03626064,追溯注册:2018年8月。