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针对低社会经济地位人群烟草依赖管理的个性化多成分干预措施:一项系统评价与荟萃分析。

Personalised multicomponent interventions for tobacco dependence management in low socioeconomic populations: a systematic review and meta-analysis.

作者信息

Huynh Nina, Tariq Saania, Charron Catherine, Hayes Tavis, Bhanushali Onkar, Kaur Tina, Jama Sadia, Ambade Preshit, Bignell Ted, Hegarty Terry, Shorr Risa, Pakhale Smita

机构信息

The Bridge Engagement Centre, Ottawa, Ontario, Canada.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

出版信息

J Epidemiol Community Health. 2022 May 27;76(8):716-29. doi: 10.1136/jech-2021-216783.

Abstract

BACKGROUND

There remains a disproportionally high tobacco smoking rate in low-income populations. Multicomponent tobacco dependence interventions in theory are effective. However, which intervention components are necessary to include for low socioeconomic status (SES) populations is still unknown.

OBJECTIVE

To assess the effectiveness of multicomponent tobacco dependence interventions for low SES and create a checklist tool examining multicomponent interventions.

METHODS

EMBASE and MEDLINE databases were searched to identify randomised controlled trials (RCTs) published with the primary outcome of tobacco smoking cessation measured at 6 months or post intervention. RCTs that evaluated tobacco dependence management interventions (for reduction or cessation) in low SES (experience of housing insecurity, poverty, low income, unemployment, mental health challenges, illicit substance use and/or food insecurity) were included. Two authors independently abstracted data. Random effects meta-analysis and post hoc sensitivity analysis were performed.

RESULTS

Of the 33 included studies, the number of intervention components ranged from 1 to 6, with smoking quit rates varying between 1% and 36.6%. Meta-analysis revealed that both the 6-month and 12-month outcome timepoints, multicomponent interventions were successful in achieving higher smoking quit rates than the control (OR 1.64, 95% Cl 1.41 to 1.91; OR 1.74, 95% Cl 1.30 to 2.33). Evidence of low heterogeneity in the effect size was observed at 6-month (I=26%) and moderate heterogeneity at 12-month (I=56%) outcomes.

CONCLUSION

Multicomponent tobacco dependence interventions should focus on inclusion of social support, frequency and duration of components. Employing community-based participatory-action research approach is essential to addressing underlying psychosocioeconomic-structural factors, in addition to the proven combination pharmacotherapies.

PROSPERO REGISTRATION NUMBER

CRD42017076650.

摘要

背景

低收入人群的吸烟率仍然高得不成比例。理论上,多成分烟草依赖干预措施是有效的。然而,对于社会经济地位(SES)较低的人群,哪些干预成分是必要的,目前仍不清楚。

目的

评估多成分烟草依赖干预措施对低SES人群的有效性,并创建一个检查多成分干预措施的清单工具。

方法

检索EMBASE和MEDLINE数据库,以识别发表的随机对照试验(RCT),其主要结局为在6个月或干预后测量的戒烟情况。纳入评估低SES(有住房不安全、贫困、低收入、失业、心理健康挑战、非法药物使用和/或粮食不安全经历)人群烟草依赖管理干预措施(用于减少或戒烟)的RCT。两位作者独立提取数据。进行随机效应荟萃分析和事后敏感性分析。

结果

在纳入的33项研究中,干预成分的数量从1到6不等,戒烟率在1%至36.6%之间。荟萃分析显示,在6个月和12个月的结局时间点,多成分干预措施在实现更高的戒烟率方面比对照组更成功(OR 1.64,95%CI 1.41至1.91;OR 1.74,95%CI 1.30至2.33)。在6个月时观察到效应大小异质性较低的证据(I=26%),在12个月时观察到中等异质性(I=56%)。

结论

多成分烟草依赖干预措施应注重纳入社会支持、成分的频率和持续时间。除了经过验证的联合药物疗法外,采用基于社区的参与性行动研究方法对于解决潜在的心理社会经济结构因素至关重要。

PROSPERO注册号:CRD42017076650。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6901/9279829/9cb18823516c/jech-2021-216783f01.jpg

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