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法语版蒙特利尔认知评估 5 分钟版的验证,这是一种用于电话管理的简短认知筛查测试。

Validation in French of the Montreal Cognitive Assessment 5-Minute, a brief cognitive screening test for phone administration.

机构信息

Inserm, Lille Neurosciences and Cognition, CHU de Lille, University Lille, 59000 Lille, France; Neurology and Movement Disorders, Lille University Medical Center, Lille, France.

Clinical Investigation Center, Lille University Medical Center, Lille, France.

出版信息

Rev Neurol (Paris). 2021 Oct;177(8):972-979. doi: 10.1016/j.neurol.2020.09.002. Epub 2021 Jan 19.

Abstract

BACKGROUND

The prevalence of cognitive impairment and dementia is high and steadily increasing. Early detection of cognitive decline is crucial since some interventions can reduce the risk of progression to dementia. However, there is a lack of manageable scales for assessing cognitive functions outside specialized consultations. Recently, the MoCA-5min, a short version of the Montreal Cognitive assessment (MoCA), phone-administered, was validated for screening for vascular cognitive impairment. The aim of the present study was to validate the MoCA-5min in French in diverse clinical populations.

METHODS

The Cantonese version of the MoCA-5min was adapted for French language. Healthy volunteers and patients with possible or established cognitive impairment (Alzheimer's disease or related disorders, Parkinson's disease, Huntington's disease, type-2 diabetes) participated in the study. The original MoCA and the MoCA-5min were administered, by phone, with a 30-day interval. Alternate forms were used to reduce learning effects.

RESULTS

The scores of the original MoCA and MoCA-5min correlated significantly (Spearman rho=0.751, P<0.0001, 95% confidence interval 0.657 to 0.819). Internal consistency was good (Cronbach alpha=0.795). The area under the ROC curve was 0.870 and the optimal cut-off value for separating patients with and without cognitive impairment with the MoCA-5min was≤27 with 87.32% sensitivity and 76.09% specificity. Interrater and test-retest reliability were adequate.

CONCLUSION

This study demonstrates that the French version of the MoCA-5min is a valid and reliable scale for detecting cognitive impairment in different clinical populations. It is administrable by phone and thus suitable for remote assessment as well as for large-scale screening and epidemiological studies.

摘要

背景

认知障碍和痴呆的患病率很高且呈稳步上升趋势。早期发现认知能力下降至关重要,因为某些干预措施可以降低发展为痴呆的风险。然而,在专门的咨询之外,缺乏用于评估认知功能的易于管理的量表。最近,经过电话管理验证,可用于筛查血管性认知障碍的蒙特利尔认知评估(MoCA)的短版本 MoCA-5min 被验证。本研究的目的是在不同的临床人群中验证法语版 MoCA-5min。

方法

将 MoCA-5min 的粤语版本改编为法语。健康志愿者和可能或已确诊认知障碍的患者(阿尔茨海默病或相关疾病、帕金森病、亨廷顿病、2 型糖尿病)参与了这项研究。通过电话以 30 天的间隔分别进行原始 MoCA 和 MoCA-5min 的测试。使用交替形式以减少学习效果。

结果

原始 MoCA 和 MoCA-5min 的分数呈显著相关(Spearman rho=0.751,P<0.0001,95%置信区间为 0.657 至 0.819)。内部一致性良好(Cronbach alpha=0.795)。ROC 曲线下面积为 0.870,MoCA-5min 区分有认知障碍和无认知障碍患者的最佳截断值为≤27,其敏感性为 87.32%,特异性为 76.09%。评分者间信度和重测信度良好。

结论

本研究表明,法语版 MoCA-5min 是一种用于检测不同临床人群认知障碍的有效且可靠的量表。它可以通过电话进行管理,因此适用于远程评估以及大规模筛查和流行病学研究。

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