Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Port Road, Adelaide, SA5000, Australia.
Wakefield Orthopaedic Clinic, Adelaide, SA5000, Australia.
Int Orthop. 2021 Mar;45(3):593-604. doi: 10.1007/s00264-021-04949-y. Epub 2021 Jan 22.
Initial stability of uncemented acetabular components in total hip arthroplasty (THA) is important for osseointegration and potentially enhanced by screw fixation. We used Australian Orthopaedic Association National Joint Replacement Registry data to determine whether screw usage influences uncemented acetabular component survival.
Primary THA with uncemented acetabular components performed for osteoarthritis from 1999 to 2018 was included. Survivorship was calculated using Kaplan-Meier estimates of cumulative percent revision (CPR). Comparisons used Cox proportional hazards method. An instrumental variable analysis adjusted for surgeon preference for screws as a confounding factor was used.
Three hundred thirty thousand one hundred ninety-two THAs were included (31.8% with screws, 68.2% without). Two hundred twenty thousand six hundred seven were included in the instrumental variable analysis. Revision rate of acetabular components (all causes) was higher with screws during the first six years (hazard ratio (HR) = 1.45 (95% CI 1.34, 1.57), p < 0.001) and lower thereafter (HR = 0.81 (95% CI 0.67, 0.98), p = 0.027). Revision rate of acetabular components for loosening was higher with screws over the entire study period (HR = 1.73 (95% CI 1.51, 1.98), p < 0.001). Overall THA revision rate was higher with screws during the first six years (HR = 1.20 (95% CI 1.15, 1.26), p < 0.001) but lower thereafter (HR = 0.89 (95% CI 0.81, 0.98), p = 0.020). Revision rate for dislocation was higher with screws over the entire period (HR = 1.16 (95% CI 1.06, 1.26), p < 0.001). Instrumental variable analysis revealed higher revision rates with acetabular screws in the first six years. (HR = 1.18 (95% CI 1.09-1.29), p < 0.001).
Screws did not confer a protective effect against acetabular loosening and were not associated with long-term negative consequences.
全髋关节置换术(THA)中非骨水泥髋臼组件的初始稳定性对于骨整合很重要,并且可能通过螺钉固定得到增强。我们使用澳大利亚矫形协会国家关节置换登记处的数据来确定螺钉的使用是否会影响非骨水泥髋臼组件的存活率。
纳入了 1999 年至 2018 年因骨关节炎进行的初次 THA,使用 Kaplan-Meier 估计的累计百分比修订率(CPR)计算存活率。使用 Cox 比例风险方法进行比较。使用调整了外科医生对螺钉偏好的工具变量分析来调整混杂因素。
共纳入 331920 例 THA(31.8%使用螺钉,68.2%未使用螺钉)。220670 例纳入工具变量分析。髋臼组件(所有原因)的翻修率在最初 6 年内使用螺钉时更高(风险比(HR)=1.45(95%置信区间 1.34,1.57),p<0.001),此后较低(HR=0.81(95%置信区间 0.67,0.98),p=0.027)。在整个研究期间,髋臼组件因松动而翻修的比率使用螺钉时更高(HR=1.73(95%置信区间 1.51,1.98),p<0.001)。在最初 6 年内,使用螺钉时的总体 THA 翻修率更高(HR=1.20(95%置信区间 1.15,1.26),p<0.001),但此后较低(HR=0.89(95%置信区间 0.81,0.98),p=0.020)。在整个时期,使用螺钉时脱位的翻修率更高(HR=1.16(95%置信区间 1.06,1.26),p<0.001)。工具变量分析显示,在前 6 年中,髋臼螺钉的翻修率更高(HR=1.18(95%置信区间 1.09-1.29),p<0.001)。
螺钉并没有提供对髋臼松动的保护作用,并且与长期的不良后果无关。