Vishnevskaia E E, Shelkovich S E
Vopr Onkol. 1988;34(2):181-6.
The paper discusses the data on 262 cases of cervical carcinoma (adenocarcinoma--138; squamous cell carcinoma--124). The pathogenetic and clinical characteristics, particularly localization, growth and dissemination, of the two malignancies were compared. More than a third of cervical carcinoma patients revealed disturbances in fat and carbohydrate metabolism and ovarian and menstrual function. The endometrium and ovaries were involved in half of them. No such involvement was observed in squamous cell carcinoma patients. Nor any significant disorders occurred in the neuroendocrine system. The hormone dependence of cervical adenocarcinoma and the common nature of its pathogenetic features and those of adenocarcinoma of the endometrium are suggested.
该论文讨论了262例宫颈癌病例的数据（腺癌——138例；鳞状细胞癌——124例）。比较了这两种恶性肿瘤的发病机制和临床特征，特别是定位、生长和扩散情况。超过三分之一的宫颈癌患者出现脂肪和碳水化合物代谢以及卵巢和月经功能紊乱。其中一半患者的子宫内膜和卵巢受到累及。鳞状细胞癌患者未观察到此类累及情况。神经内分泌系统也未出现任何明显紊乱。提示宫颈癌具有激素依赖性，且其发病机制特征与子宫内膜腺癌具有共同性。
