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前列腺癌的外照射治疗:当前的研究趋势和热点是什么?

External beam radiotherapy for prostate cancer: What are the current research trends and hotspots?

机构信息

Department of Radiation Oncology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Graduate School of Peking Union Medical College, Beijing, China.

出版信息

Cancer Med. 2021 Jan;10(2):772-782. doi: 10.1002/cam4.3700. Epub 2021 Jan 21.

DOI:10.1002/cam4.3700
PMID:33480190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7877352/
Abstract

BACKGROUND

The external beam radiotherapy (EBRT) applied for prostate cancer (PCa) has been one of the most important and hottest research fields over recent decades. This study aimed to explore the research hotspots of EBRT in PCa and help the researchers have a clear and intuitive reference basis for later researches.

METHODS

The literature scientometric analysis related to "EBRT applied for PCa" was conducted via the Web of Science Core Collection from 2010 to 2019. The Microsoft Office Excel 2019 and CiteSpace V. 5.7.R1 software were introduced for visualizing and analyzing the data.

RESULTS

A total of 7860 relevant papers were extracted and downloaded. A total of 7828 papers were extracted and analyzed after data cleansing by CiteSpace. The tendency of published papers was comprehensively increasing from 2010 to 2019. Among all 73 countries/regions, USA published the most papers, accounting for 39%, which was the most active contributor with most publications. Australia (Centrality: 0.18), England (Centrality: 0.12) were cooperating most cohesively with other countries. Univ Toronto was the most productive institute (229), while Harvard Univ (Centrality: 0.67) had extensive collaborations with other institutes. The International journal of Radiation Oncology Biology Physics had the largest number of publications and the highest number of co-citations. Briganti A had the largest volume of publications. D'Amico AV had the highest number of co-citations. Four latest and largest clusters were identified as oligometastases, salvage therapy (SRT), prostate-specific membrane antigen (PSMA), and hypofractionation. Thirteen references became strongest burst citations lasting until 2019. The studies of "oligometastases," "SRT," "PSMA," "hypofractionation," "postoperative radiotherapy," and "dose and fraction regimen changes" were prevailing in the recent years.

CONCLUSION

The "oligometastases," "SRT," "PSMA," "hypofractionation," "postoperative radiotherapy," and "dose and fraction regimen changes" may be the state-of-art research frontiers, and related studies will advance in this field over time.

摘要

背景

外照射放射治疗(EBRT)在前列腺癌(PCa)中的应用一直是近几十年来最重要和最热门的研究领域之一。本研究旨在探讨 EBRT 在 PCa 中的研究热点,为后来的研究提供清晰直观的参考依据。

方法

通过 Web of Science 核心合集,对 2010 年至 2019 年期间与“EBRT 应用于 PCa”相关的文献进行科学计量学分析。采用 Microsoft Office Excel 2019 和 CiteSpace V. 5.7.R1 软件对数据进行可视化和分析。

结果

共提取并下载了 7860 篇相关论文。通过 CiteSpace 数据清洗,共提取并分析了 7828 篇论文。2010 年至 2019 年,发表论文的趋势呈全面增长态势。在所有 73 个国家/地区中,美国发表的论文最多,占 39%,是发表论文最多、最活跃的国家。澳大利亚(中心度:0.18)、英国(中心度:0.12)与其他国家的合作最为紧密。多伦多大学是最具生产力的机构(229),而哈佛大学(中心度:0.67)与其他机构的合作最为广泛。《国际放射肿瘤学、生物学、物理学杂志》发表的论文数量最多,被引频次最高。Briganti A 发表的论文数量最多。D'Amico AV 的被引频次最高。确定了四个最新和最大的聚类为寡转移、挽救性治疗(SRT)、前列腺特异性膜抗原(PSMA)、和低分割。13 篇参考文献成为截至 2019 年最强的爆发引文。近年来,“寡转移”、“SRT”、“PSMA”、“低分割”、“术后放疗”和“剂量和分割方案变化”的研究成为主流。

结论

“寡转移”、“SRT”、“PSMA”、“低分割”、“术后放疗”和“剂量和分割方案变化”可能是当前的研究前沿,随着时间的推移,相关研究将在该领域不断推进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/ac56637391f2/CAM4-10-772-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/d29da7eb9754/CAM4-10-772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/73c364ca18e9/CAM4-10-772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/9bfa2cee1650/CAM4-10-772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/63b833d78740/CAM4-10-772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/8ae87233c1e0/CAM4-10-772-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/ac56637391f2/CAM4-10-772-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/d29da7eb9754/CAM4-10-772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/73c364ca18e9/CAM4-10-772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/9bfa2cee1650/CAM4-10-772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/63b833d78740/CAM4-10-772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/8ae87233c1e0/CAM4-10-772-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c35e/7877352/ac56637391f2/CAM4-10-772-g006.jpg

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