Department of Health and Nutrition, Faculty of Health Management, Nagasaki International University, Nagasaki, Japan -
Graduate School of Nutritional Sciences, Nakamura Gakuen University, Fukuoka, Japan -
J Sports Med Phys Fitness. 2021 Dec;61(12):1661-1667. doi: 10.23736/S0022-4707.21.12001-8. Epub 2021 Jan 22.
No study has previously investigated insulin resistance in collegiate baseball players. The purposes of this study were to examine: 1) the insulin resistance; and 2) the usefulness of the adiponectin/leptin (A/L) ratio compared with the homeostasis model assessment of insulin resistance (HOMA-IR) for assessing insulin resistance in collegiate baseball players.
Twenty collegiate baseball players with abdominal obesity (AO group) defined by a waist circumference (WC) ≥85 cm, 65 lean baseball players with a WC<85 cm (L group), and 20 controls who were sedentary for at least 1 year (C group) were compared. The Body Mass Index, WC, systolic and diastolic blood pressures, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, apolipoprotein B, insulin, leptin, adiponectin, and high-sensitivity C-reactive protein (hs-CRP) were measured.
The AO group had a significantly higher insulin level, HOMA-IR, and leptin level, and lower A/L ratio than the L and C groups. The AO group had a significantly higher prevalence of insulin resistance (50%) than the L (14%) group. The A/L ratio was significantly negatively correlated with body weight, Body Mass Index, WC, triglycerides, triglycerides/HDL-C ratio, apolipoprotein B, hs-CRP, insulin, HOMA-IR, and leptin, and positively correlated with HDL-C, whereas HOMA-IR was significantly positively correlated with body weight, Body Mass Index, WC, systolic and diastolic blood pressures, fasting plasma glucose, and insulin, and negatively correlated with adiponectin and the A/L ratio. In the forward stepwise multiple regression analysis, WC, triglycerides, and hs-CRP were the significant determinants for the A/L ratio, whereas diastolic blood pressure and WC were the significant determinants for HOMA-IR. This model explained 53.7% of the variance in the A/L ratio and 13.6% of the variance in HOMA-IR.
The present study suggested that the baseball players with abdominal obesity had a significantly higher prevalence of insulin resistance than the lean baseball group. The A/L ratio may be more useful than HOMA-IR to accurately assess insulin resistance in male collegiate baseball players.
之前没有研究调查过大学生棒球运动员的胰岛素抵抗情况。本研究旨在探讨：1）胰岛素抵抗；2）脂联素/瘦素（A/L）比值与稳态模型评估的胰岛素抵抗（HOMA-IR）相比，在评估大学生棒球运动员胰岛素抵抗方面的作用。
比较 20 名腹部肥胖的大学生棒球运动员（AO 组，腰围≥85cm）、65 名腰围<85cm 的瘦棒球运动员（L 组）和 20 名至少久坐 1 年的对照组（C 组）。测量体重指数、腰围、收缩压和舒张压、空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇、载脂蛋白 B、胰岛素、瘦素、脂联素和高敏 C 反应蛋白（hs-CRP）。
AO 组的胰岛素水平、HOMA-IR 和瘦素水平显著高于 L 组和 C 组，A/L 比值显著低于 L 组和 C 组。AO 组的胰岛素抵抗发生率（50%）显著高于 L 组（14%）。A/L 比值与体重、体重指数、腰围、甘油三酯、甘油三酯/高密度脂蛋白胆固醇比值、载脂蛋白 B、hs-CRP、胰岛素、HOMA-IR 和瘦素呈显著负相关，与高密度脂蛋白胆固醇呈显著正相关，而 HOMA-IR 与体重、体重指数、腰围、收缩压和舒张压、空腹血糖和胰岛素呈显著正相关，与脂联素和 A/L 比值呈显著负相关。在逐步多元回归分析中，腰围、甘油三酯和 hs-CRP 是 A/L 比值的显著决定因素，而舒张压和腰围是 HOMA-IR 的显著决定因素。该模型解释了 A/L 比值变异的 53.7%和 HOMA-IR 变异的 13.6%。
本研究表明，腹部肥胖的棒球运动员的胰岛素抵抗发生率显著高于瘦棒球运动员。与 HOMA-IR 相比，A/L 比值可能更能准确评估男性大学生棒球运动员的胰岛素抵抗。
