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发热性中性粒细胞减少症:在社区医院急诊科缩短抗生素给药时间。

Febrile Neutropenia: Decreasing Time to Antibiotic Administration in a Community Hospital Emergency Department.

机构信息

Duke Cancer Center.

出版信息

Clin J Oncol Nurs. 2021 Feb 1;25(1):23-26. doi: 10.1188/21.CJON.23-26.

Abstract

Febrile neutropenia, a serious complication of cytotoxic chemotherapy, is an oncologic emergency associated with high rates of morbidity and mortality. Fever is often the only clinical sign of an underlying infection in neutropenic patients with cancer. Prompt treatment with empiric broad-spectrum antibiotics is crucial to ensuring best outcomes for patients; practice guidelines recommend antibiotic administration within one hour of fever onset. A quality improvement initiative to improve time to antibiotic administration among patients with febrile neutropenia presenting to a community hospital emergency department is described in this article.

摘要

发热性中性粒细胞减少症是细胞毒性化疗的严重并发症,是一种与高发病率和死亡率相关的肿瘤急症。发热是癌症中性粒细胞减少患者潜在感染的唯一临床征象。及时给予经验性广谱抗生素治疗对于确保患者获得最佳疗效至关重要;临床实践指南建议在发热发作后 1 小时内给予抗生素。本文描述了一项旨在改善社区医院急诊科发热性中性粒细胞减少症患者抗生素给药时间的质量改进计划。

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