Maes M, De Ruyter M, Claes R, Suy E
University Hospital, Department of Psychiatry, Edegem, Belgium.
Acta Psychiatr Scand. 1988 Jan;77(1):27-31. doi: 10.1111/j.1600-0447.1988.tb05072.x.
The Zung Self-Rating Depression Scale (SDS) was presented to 99 depressed inpatients. The patients were categorized according to DSM-III as suffering from minor depression, major depression without melancholia and major depression with melancholia and/or with psychotic features. Differences in self-reported symptoms between these categories were studied with multivariate statistical techniques including linear discriminant analysis (LDA) and statistical isolinear multiple components analysis (SIMCA). Patients with minor depression rate themselves significantly less depressed than those with major depression. Patients with major depression without melancholia are less depressed than those with melancholia and/or psychotic features. The three DSM-III depressive categories can be regarded as belonging to a clinical continuum in which they form relevant levels with quantitative differences in self-reported symptoms. These differences are not only defined by gradual shiftings in the overall severity of illness, but also by quantitative differences in the severity of some target symptoms, i.e. agitation, retardation, diurnal variation, loss of libido, fatiguability, insomnia, anorexia, sadness and anhedonia.
将zung自评抑郁量表（SDS）应用于99名住院抑郁症患者。根据《精神疾病诊断与统计手册》第三版（DSM-III），这些患者被分为患有轻度抑郁症、无抑郁发作的重度抑郁症以及伴有抑郁发作和/或精神病性特征的重度抑郁症。采用多元统计技术，包括线性判别分析（LDA）和统计等线性多成分分析（SIMCA），研究这些类别之间自我报告症状的差异。轻度抑郁症患者自评的抑郁程度明显低于重度抑郁症患者。无抑郁发作的重度抑郁症患者的抑郁程度低于伴有抑郁发作和/或精神病性特征的患者。DSM-III中的这三种抑郁类别可被视为属于一个临床连续体，在这个连续体中，它们形成了具有自我报告症状数量差异的相关水平。这些差异不仅由疾病总体严重程度的逐渐变化所定义，还由一些目标症状严重程度的数量差异所定义，即激越、迟缓、昼夜变化、性欲减退、易疲劳、失眠、厌食、悲伤和快感缺失。
