General Surgery Department, Mansoura University Hospitals, Mansoura University, 60 El-Gomhouria Street, Mansoura, 35516, Dakahlia, Egypt.
General Surgery Department, Qasr Al-Ainy Hospitals, Cairo University, Cairo, Egypt.
World J Surg. 2021 Apr;45(4):1210-1221. doi: 10.1007/s00268-020-05919-y. Epub 2021 Jan 22.
Treatment of anismus usually starts with biofeedback therapy and injection of botulinum toxin in the puborectalis muscle (PRM). Patients refractory to conservative treatment may require surgery. The present cohort study aimed to assess a combined technique of partial division of PRM and tailored lateral internal sphincterotomy (LIS) in treatment of anismus.
Patients with anismus who failed conservative treatments were assessed clinically and with high-resolution anal manometry (HRAM), EMG, defecography, and underwent combined partial division of PRM on one side and tailored LIS on the contralateral side. Main outcome measures were improvement in symptoms and quality of life, changes in HRAM and defecography postoperatively, complications, and patient satisfaction.
A total of 73 patients (61 male) of a mean age of 37 years were included to the study. In total, 89% of patients showed a significant improvement in symptoms at 12 months postoperatively. The mean modified Altomare score decreased significantly (p < 0.0001) from 16.4 ± 1.7 to 6.6 ± 1 at 12 months postoperatively. There was a significant increase in the mental and physical components of quality of life at 12 months postoperatively. The numbers of patients with positive findings of anismus in postoperative defecography, EMG, and balloon expulsion test were significantly less than before surgery. The mean total satisfaction score was 86.5 ± 8.7. Five (6.5%) patients developed minor complications.
Partial division of puborectalis muscle combined with LIS is an effective technique in the management of anal hypertonia-associated anismus with satisfactory results and low incidence of complications.
肛肌失弛缓症的治疗通常始于生物反馈疗法和耻骨直肠肌(PRM)内注射肉毒杆菌毒素。对保守治疗无反应的患者可能需要手术。本队列研究旨在评估 PRM 部分切开术联合改良外侧内括约肌切开术(LIS)治疗肛肌失弛缓症的疗效。
对经保守治疗无效的肛肌失弛缓症患者进行临床评估,并进行高分辨率肛门测压(HRAM)、肌电图(EMG)、排粪造影检查,对一侧 PRM 进行部分切开术,对对侧 PRM 进行改良 LIS。主要观察指标为症状和生活质量改善、术后 HRAM 和排粪造影变化、并发症和患者满意度。
共纳入 73 例(61 例男性)平均年龄 37 岁的患者。术后 12 个月,89%的患者症状明显改善。改良 Altomare 评分从术前的 16.4±1.7 分显著下降至术后 12 个月的 6.6±1 分(p<0.0001)。术后 12 个月,生活质量的心理和生理成分明显增加。术后排粪造影、EMG 和球囊排出试验中肛肌失弛缓症阳性的患者数量明显少于术前。总满意度评分为 86.5±8.7。5 例(6.5%)患者出现轻微并发症。
PRM 部分切开术联合 LIS 是一种治疗与肛门张力过高相关的肛肌失弛缓症的有效方法,疗效满意,并发症发生率低。