Department of Ophthalmology & Visual Sciences, Prince of Wales Hospital & Alice Ho Miu Ling Nethersole Hospital, Hong Kong SAR.
Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR.
Asia Pac J Ophthalmol (Phila). 2021 Jan 19;10(4):388-396. doi: 10.1097/APO.0000000000000369.
We performed a systematic review on 3 major types of scleral-fixated intraocular lens (SFIOL) implantations and conducted subgroup analyses on pediatric population and subjects with Marfan syndrome.
Systematic review.
We performed a search in PubMed, Ovid MEDLINE, and Embase for English language articles with keywords "(sutured intraocular lens) OR (SFIOL) OR (sutureless intraocular lens) OR (glued intraocular lens) OR (intrascleral intraocular lens) OR (SFIOL)" through October 16, 2019. Articles reporting individual outcomes after SFIOL were included in this systematic review. Recorded outcome measures included intraoperative and postoperative complications, endothelial cell changes, and intraocular lens-related outcomes.
Our search yielded 217 papers. After removing duplicated and irrelevant reports, we included 57 articles involving 2624 eyes. The mean age at operation was 51.47 ± 25.62 years. Sutured SFIOL was most commonly reported in all subjects with Marfan syndrome and 92.87% of pediatric patients. The pooled intraoperative complication rate was 6.65%. Minor anterior chamber hemorrhage was the most common intraoperative (1.92%) and postoperative complication (13.93%). Optic capture was the top intraocular lens (IOL)-related complication (4.47%). The overall mean endothelial cell loss was 8.95% at 16.77 ± 11.04 months. Overall 11.99% of SFIOLs were decentred with a mean distance of 0.49 ± 0.40 mm and a mean degree of tilt by 4.11 ± 3.03°.
Glued SFIOL had the fewest IOL-related complications and the lowest endothelial cell loss. Sutured SFIOL carried the highest IOL-related complications, whereas sutureless, glueless SFIOL was associated with the greatest endothelial cell loss.
我们对 3 种巩膜固定型人工晶状体（SFIOL）植入物进行了系统评价，并对小儿和马凡综合征患者进行了亚组分析。
系统评价。
我们在 PubMed、Ovid MEDLINE 和 Embase 中使用关键词“（缝合型人工晶状体）或（SFIOL）或（无缝合型人工晶状体）或（粘固型人工晶状体）或（巩膜内人工晶状体）或（SFIOL）”进行了搜索，检索时间截至 2019 年 10 月 16 日。本系统评价纳入了报道 SFIOL 术后个体结局的研究。记录的结局指标包括术中及术后并发症、内皮细胞变化和人工晶状体相关结局。
我们的搜索结果为 217 篇文献。剔除重复和不相关的报告后，我们纳入了 57 篇涉及 2624 只眼的文章。手术时的平均年龄为 51.47±25.62 岁。巩膜固定型人工晶状体在所有马凡综合征患者和 92.87%的小儿患者中最常被报道。术中并发症总发生率为 6.65%。轻微前房出血是最常见的术中（1.92%）和术后并发症（13.93%）。光学捕获是最常见的人工晶状体（IOL）相关并发症（4.47%）。总的来说，术后 16.77±11.04 个月时，内皮细胞丢失的平均值为 8.95%。总体上有 11.99%的 SFIOL 出现偏心，平均距离为 0.49±0.40mm，平均倾斜度为 4.11±3.03°。
粘固型 SFIOL 的 IOL 相关并发症最少，内皮细胞丢失率最低。缝合型 SFIOL 与最高的 IOL 相关并发症相关，而无缝合型、无粘固型 SFIOL 则与最大的内皮细胞丢失相关。
