School of Chemical Sciences, National Institute of Science Education and Research (NISER), HBNI, Bhubaneswar 752050, Odisha, India.
Org Biomol Chem. 2021 Feb 18;19(6):1386-1394. doi: 10.1039/d0ob02515a.
One-pot synthesis of Robinson annulated 3-aryl-cyclohexenones from allyl alcohols and ketones using palladium is reported. Long chain aliphatic or aryl substitutions at the C1 position of allyl alcohol result in the formation of 1,5-diketone products. This simple one-pot method avoids the use of highly electrophilic vinyl ketones.
本文报道了一种使用钯的一锅法从烯丙醇和酮合成 Robinson 稠合的 3-芳基环己烯酮的方法。在烯丙醇的 C1 位具有长链脂肪族或芳基取代基时，会生成 1,5-二酮产物。这种简单的一锅法避免了使用高亲电的乙烯酮。
