Kumar Gautam, Roy Sourav, Chatterjee Indranil
Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab-140001, India.
Org Biomol Chem. 2021 Feb 18;19(6):1230-1267. doi: 10.1039/d0ob02478c.
A series of boron based Lewis acids have been reported to date, but among them, tris(pentafluorophenyl)borane (BCF) has gained the most significant attention in the synthetic chemistry community. The viability of BCF as a potential Lewis acid catalyst has been vastly explored in organic and materials chemistry due to its thermal stability and commercial availability. Most explorations of BCF chemistry in organic synthesis has occurred in the last two decades and many new catalytic reactivities are currently under investigation. This review mainly focuses on recent reports from 2018 onwards and provides a concise knowledge to the readers about the role of BCF in metal-free catalysis. The review has mainly been categorized by different types of organic transformation mediated through BCF catalysis for the C-C and C-heteroatom bond formation.
迄今为止，已经报道了一系列硼基路易斯酸，但其中三（五氟苯基）硼烷（BCF）在合成化学领域引起了最为广泛的关注。由于其热稳定性和商业可得性，BCF作为潜在路易斯酸催化剂的可行性在有机化学和材料化学中得到了广泛探索。在过去二十年中，有机合成领域对BCF化学进行了大量探索，目前许多新的催化反应活性仍在研究中。本综述主要关注2018年以来的最新报道，并向读者简要介绍BCF在无金属催化中的作用。该综述主要根据通过BCF催化介导的不同类型有机转化进行分类，这些转化用于形成碳-碳键和碳-杂原子键。
