Esser Marissa B, Pickens Cassandra M, Guy Gery P, Evans Mary E
Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Division of Overdose Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Prev Med. 2021 Feb;60(2):169-178. doi: 10.1016/j.amepre.2020.08.025.
The use of multiple substances heightens the risk of overdose. Multiple substances, including alcohol, are commonly found among people who experience overdose-related mortality. However, the associations between alcohol use and the use of a range of other substances are often not assessed. Therefore, this study examines the associations between drinking patterns (e.g., binge drinking) and other substance use in the U.S., the concurrent use of alcohol and prescription drug misuse, and how other substance use varies by binge-drinking frequency.
Past 30-day alcohol and other substance use data from the 2016-2018 National Survey on Drug Use and Health were analyzed in 2020 among 169,486 U.S. respondents aged ≥12 years.
The prevalence of other substance use ranged from 6.0% (nondrinkers) to 24.1% (binge drinkers). Among people who used substances, 22.2% of binge drinkers reported using substances in 2 additional substance categories. Binge drinking was associated with 4.2 (95% CI=3.9, 4.4) greater adjusted odds of other substance use than nondrinking. Binge drinkers were twice as likely to report concurrent prescription drug misuse while drinking as nonbinge drinkers. The prevalence of substance use increased with binge-drinking frequency.
Binge drinking was associated with other substance use and concurrent prescription drug misuse while drinking. These findings can guide the implementation of a comprehensive approach to prevent binge drinking, substance misuse, and overdoses. This might include population-level strategies recommended by the Community Preventive Services Task Force to prevent binge drinking (e.g., increasing alcohol taxes and regulating alcohol outlet density).
使用多种物质会增加过量用药的风险。在与过量用药相关的死亡人群中，经常会发现包括酒精在内的多种物质。然而，酒精使用与一系列其他物质使用之间的关联往往未得到评估。因此，本研究考察了美国饮酒模式（如暴饮）与其他物质使用之间的关联、酒精与处方药滥用的同时使用情况，以及其他物质使用如何因暴饮频率而异。
2020年对2016 - 2018年全国药物使用和健康调查中169486名年龄≥12岁的美国受访者过去30天的酒精及其他物质使用数据进行了分析。
其他物质使用的患病率从6.0%（不饮酒者）到24.1%（暴饮者）不等。在使用物质的人群中，22.2%的暴饮者报告在另外两个物质类别中使用物质。与不饮酒相比，暴饮与其他物质使用的调整优势比高4.2（95%置信区间=3.9, 4.4）。暴饮者在饮酒时报告同时滥用处方药的可能性是非暴饮者的两倍。物质使用的患病率随暴饮频率增加而上升。
暴饮与其他物质使用以及饮酒时同时滥用处方药有关。这些发现可为实施预防暴饮、物质滥用和过量用药的综合方法提供指导。这可能包括社区预防服务工作组推荐的预防暴饮的人群层面策略（如提高酒精税和规范酒精销售点密度）。
