Unthank J L, Bohlen H G
Department of Physiology, Indiana University School of Medicine, Indianapolis 46223.
Am J Physiol. 1988 Mar;254(3 Pt 1):G389-98. doi: 10.1152/ajpgi.1988.254.3.G389.
The pathways through which lymph is propelled from the mucosal, submucosal, and muscle layer lymphatics of the small intestine, the interconnections between these layers, and the location of lymphatic valves within these layers were studied. Injections of fluid into a single lacteal or submucosal lymphatic of rats, rabbits, dogs, and cats spread in all directions through the submucosal lymphatics and into laceteals but did not enter the lymphatics of the muscle layer. Injections into muscle layer lymphatics also spread in all directions but in no case entered the submucosal lymphatics. The submucosal and muscle layer lymphatics join within the bowel wall near the mesenteric border to form collecting lymphatics characterized by valves and spontaneous contractions. These data indicate that lymphatics of the mucosa and submucosa form a syncytium independent of the muscle layer lymphatics and that few if any valves exist within these lymphatic networks. Cycling lacteal pressures were measured when intestinal motility was present but not when motility was abolished, suggesting that intestinal motility might have a role in lymph propulsion.
研究了淋巴从小肠黏膜、黏膜下层和肌层淋巴管排出的途径，这些层之间的相互连接，以及这些层内淋巴管瓣膜的位置。向大鼠、兔子、狗和猫的单个乳糜管或黏膜下淋巴管注射液体，液体通过黏膜下淋巴管向各个方向扩散并进入乳糜管，但未进入肌层淋巴管。向肌层淋巴管注射液体也向各个方向扩散，但在任何情况下都未进入黏膜下淋巴管。黏膜下层和肌层淋巴管在靠近肠系膜边界的肠壁内汇合，形成具有瓣膜和自发收缩特征的集合淋巴管。这些数据表明，黏膜和黏膜下层的淋巴管形成了一个独立于肌层淋巴管的合体，并且这些淋巴网络中几乎不存在瓣膜。在肠道有蠕动时测量了乳糜管压力的周期性变化，但在蠕动停止时未进行测量，这表明肠道蠕动可能在淋巴推进中起作用。
