DynaMed, EBSCO Health, Ipswich, Massachusetts, USA.
Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts, USA.
J Am Med Inform Assoc. 2021 Mar 18;28(4):766-771. doi: 10.1093/jamia/ocaa232.
Our aim was to develop an efficient search strategy for prognostic studies and clinical prediction guides (CPGs), optimally balancing sensitivity and precision while independent of MeSH terms, as relying on them may miss the most current literature.
We combined 2 Hedges-based search strategies, modified to remove MeSH terms for overall prognostic studies and CPGs, and ran the search on 269 journals. We read abstracts from a random subset of retrieved references until ≥ 20 per journal were reviewed and classified them as positive when fulfilling standardized quality criteria, thereby assembling a standard dataset used to calibrate the search strategy. We determined performance characteristics of our new search strategy against the Hedges standard and performance characteristics of published search strategies against the standard dataset.
Our search strategy retrieved 16 089 references from 269 journals during our study period. One hundred fifty-four journals yielded ≥ 20 references and ≥ 1 prognostic study or CPG. Against the Hedges standard, the new search strategy had sensitivity/specificity/precision/accuracy of 84%/80%/2%/80%, respectively. Existing published strategies tested against our standard dataset had sensitivities of 36%-94% and precision of 5%-10%.
We developed a new search strategy to identify overall prognosis studies and CPGs independent of MeSH terms. These studies are important for medical decision-making, as they identify specific populations and individuals who may benefit from interventions.
Our results may benefit literature surveillance and clinical guideline efforts, as our search strategy performs as well as published search strategies while capturing literature at the time of publication.
我们旨在开发一种用于预后研究和临床预测指南(CPG)的高效搜索策略,在不依赖 MeSH 术语的情况下,最佳地平衡敏感性和特异性,因为依赖它们可能会错过最新的文献。
我们结合了 2 种基于 Hedges 的搜索策略,对其进行了修改以去除用于总体预后研究和 CPG 的 MeSH 术语,并在 269 种期刊上运行了搜索。我们从检索到的参考文献的随机子集中阅读摘要,直到每本期刊的 20 篇以上被审查并被归类为阳性,当它们满足标准化质量标准时,从而组装一个用于校准搜索策略的标准数据集。我们确定了我们的新搜索策略相对于 Hedges 标准的性能特征,以及已发表的搜索策略相对于标准数据集的性能特征。
在我们的研究期间,我们的搜索策略从 269 种期刊中检索到了 16089 篇参考文献。154 种期刊产生了≥20 篇参考文献和≥1 篇预后研究或 CPG。相对于 Hedges 标准,新搜索策略的敏感性/特异性/精确性/准确性分别为 84%/80%/2%/80%。针对我们的标准数据集测试的现有已发表策略的敏感性为 36%-94%,而精确性为 5%-10%。
我们开发了一种新的搜索策略,用于在不依赖 MeSH 术语的情况下识别总体预后研究和 CPG。这些研究对于医疗决策很重要,因为它们确定了可能从干预中受益的特定人群和个体。
我们的结果可能会有益于文献监测和临床指南工作,因为我们的搜索策略在捕获最新文献的同时,性能与已发表的搜索策略一样好。