Department of Physical Therapy for Cardiovascular, Pulmonary Disorders and Geriatrics, Faculty of Physical Therapy, Misr University for Science and Technology, Cairo, Egypt.
Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
J Burn Care Res. 2021 Sep 30;42(5):968-974. doi: 10.1093/jbcr/irab007.
Protein catabolism is a common complication after burn injury, leading to a loss of muscle mass and a decrease in muscle strength. The present study was aimed to evaluate the efficacy of combining exercise training with protein supplementation on lean body mass and muscle strength in patients with severe burn. Sixty participants with severe burn >30% of TBSA were randomly distributed into four equal groups of 15 participants per group. Group A (Exercise and Protein) received oral protein supplementation (Inkospor X-TREME; 1.5-2.0 g/kg/d), exercise program, and traditional burn care; group B (Protein) received oral protein supplementation and traditional burn care; group C (Exercise) received exercise program and traditional burn care; and group D (Control) received traditional burn care. Lean body mass was measured using dual-energy x-ray absorptiometry, whereas muscle strength was measured using Biodex 3 Dynamometer System before treatment and 12 weeks after treatment. A significant increase in lean body mass was found in group A compared with that of group B, group C, and group D post-treatment (P < .001). Also, a significant increase was recorded in peak torque of group A compared with that of group B, group C, and group D post-treatment (P < .001). Exercise training can significantly increase lean body mass and peak torque. Protein supplementation can significantly increase lean body mass but cannot significantly increase muscle strength, whereas protein + exercise group has a great impact on lean body mass and muscle power than exercise group and protein group in burn patients.
蛋白质分解代谢是烧伤后常见的并发症,导致肌肉质量损失和肌肉力量下降。本研究旨在评估运动训练与蛋白质补充相结合对严重烧伤患者瘦体重和肌肉力量的疗效。60 名烧伤面积>30%TBSA 的严重烧伤患者被随机分为四组,每组 15 名患者。A 组(运动+蛋白质)接受口服蛋白质补充(Inkospor X-TREME;1.5-2.0 g/kg/d)、运动方案和传统烧伤护理;B 组(蛋白质)接受口服蛋白质补充和传统烧伤护理;C 组(运动)接受运动方案和传统烧伤护理;D 组(对照组)接受传统烧伤护理。治疗前和治疗 12 周后,使用双能 X 射线吸收仪测量瘦体重,使用 Biodex 3 动力计系统测量肌肉力量。与治疗后 B 组、C 组和 D 组相比,A 组的瘦体重显著增加(P<0.001)。与治疗后 B 组、C 组和 D 组相比,A 组的峰值扭矩也显著增加(P<0.001)。运动训练可以显著增加瘦体重和峰值扭矩。蛋白质补充可以显著增加瘦体重,但不能显著增加肌肉力量,而在烧伤患者中,蛋白质+运动组对瘦体重和肌肉力量的影响明显大于运动组和蛋白质组。