Medical University of Silesia in Katowice, Faculty of Medical Sciences in Katowice, Department of Epidemiology, Medyków 18, 40-752, Katowice, Poland.
Medical University of Silesia in Katowice, Faculty of Medical Sciences in Katowice, Department of Epidemiology, Medyków 18, 40-752, Katowice, Poland.
Environ Res. 2021 Apr;195:110746. doi: 10.1016/j.envres.2021.110746. Epub 2021 Jan 20.
Physical exercise in the presence of ambient air pollution may increase the absorbed dose of air pollutants. The combined effect of such exposure on cardiorespiratory function in young adults remains unclear.
To determine the acute cardiorespiratory responses in healthy young adults preforming submaximal physical exercise under exposure to high level winter-type ambient air pollution.
Healthy young males (n=30) performed two separate 15-minute submaximal exercise trials on a cycle ergometer - when air pollutants' concentrations were increased (exposure trial) and when air quality was good (control trial). Each time blood pressure, pulse oximetry, spirometry and fractional exhaled nitric oxide (FeNO) were measured at baseline, directly after exercise and after 15-min of rest.
High air pollutants concentrations were observed during exposure trials (PM 24.0-157.0 μg/m, SO 8.7-85.8 μg/m). Group-based correlation analysis showed statistically significant negative correlations between post-exercise declines in FEV/FVC and SO, PM and PM concentrations. In individual cases the decrease was recorded only in subjects who exercised under particularly high exposure, and was not related to their BMI, physical activity pattern or allergy status. In multivariate analysis SO was a statistically significant predictor of both immediate (OR: 1.09, 95%CI: 1.01-1.17) and delayed decrease in airflow (OR: 1.08, 95%CI: 1.01-1.16), and PM was also a statistically significantly explanatory variable of post-exercise decline in FEV/FVC (OR: 1.03, 95%CI: 1.00-1.06).
In young and healthy males exposure to ambient air pollution during short-term submaximal exercise is associated with a decrease in airflow (FEV/FVC) and the decrease is more apparent when the exercise takes place under particularly high exposure conditions.
在存在环境空气污染的情况下进行身体锻炼可能会增加空气污染物的吸收剂量。这种暴露对年轻成年人心肺功能的综合影响尚不清楚。
确定在冬季型高浓度环境空气污染下进行亚最大强度身体锻炼时，健康年轻成年人的急性心肺反应。
30 名健康年轻男性在自行车功量计上进行了两次单独的 15 分钟亚最大强度运动试验 - 当空气污染物浓度增加（暴露试验）和空气质量良好（对照试验）时。每次测量血压、脉搏血氧饱和度、肺活量和呼出气一氧化氮分数（FeNO），在基线、运动后直接和休息 15 分钟后。
暴露试验期间观察到高空气污染物浓度（PM 24.0-157.0μg/m，SO 8.7-85.8μg/m）。基于群组的相关分析显示，运动后 FEV/FVC 与 SO、PM 和 PM 浓度之间存在统计学上显著的负相关。在个别情况下，仅在暴露特别高的情况下运动的受试者中记录到下降，与他们的 BMI、体力活动模式或过敏状态无关。在多变量分析中，SO 是即时（OR：1.09，95%CI：1.01-1.17）和延迟气流下降（OR：1.08，95%CI：1.01-1.16）的统计学显著预测因子，PM 也是运动后 FEV/FVC 下降的统计学显著解释变量（OR：1.03，95%CI：1.00-1.06）。
在年轻健康的男性中，在短时间的亚最大强度运动期间暴露于环境空气污染与气流下降（FEV/FVC）有关，当运动发生在特别高的暴露条件下时，下降更为明显。
