School of Chemical Engineering, College of Engineering, University of Tehran, P. O. Box 11155-4563, Tehran, Iran.
School of Chemical Engineering, College of Engineering, University of Tehran, P. O. Box 11155-4563, Tehran, Iran.
Int J Biol Macromol. 2021 Mar 15;173:467-480. doi: 10.1016/j.ijbiomac.2021.01.121. Epub 2021 Jan 20.
Bacterial cellulose (BC) aerogel owing to its porous and 3D structure, poses a suitable matrix for embedding nanomaterials and polymers. Herein, BC composites comprising nano-clay/polyaniline (PANI) were synthesized via a two-step procedure. Clay nanoplatelets were dispersed in the BC membrane to form a nanofibrillated template for aniline in-situ polymerization leading to formation of a double interconnected network of electrically conductive path within the aerogel. Deposition of PANI particles on BC/clay nanocomposite was confirmed by FTIR, XRD, FESEM, and EDX techniques. The surface electrical conductivity of 0.49 S/cm was obtained for the composite aerogel comprising 5 wt% nano-clay which is 16 folds higher than that of the sample without nano-clay. Thermal stability and storage modulus of the aerogels was improved by inclusion of PANI and nano-clay. Synergistic effect of clay and polyaniline on biocompatibility and cell adhesion was obtained with no mutagenic or carcinogenic effects. The developed electrically conductive composite aerogels can be utilized as suitable scaffolds for tissue engineering applications demanding a good balance of flexibility, dimensional and thermal stability and biocompatibility.
细菌纤维素 (BC) 气凝胶由于其多孔和 3D 结构，是嵌入纳米材料和聚合物的合适基质。本文通过两步法合成了包含纳米粘土/聚苯胺 (PANI) 的 BC 复合材料。粘土纳米片分散在 BC 膜中，形成了用于苯胺原位聚合的纳米纤维模板，导致气凝胶内形成了导电路径的双互穿网络。FTIR、XRD、FESEM 和 EDX 技术证实了 PANI 颗粒沉积在 BC/粘土纳米复合材料上。包含 5wt%纳米粘土的复合材料气凝胶的表面电导率为 0.49 S/cm，是不含纳米粘土样品的 16 倍。PANI 和纳米粘土的加入提高了气凝胶的热稳定性和储能模量。粘土和聚苯胺的协同作用对细胞相容性和细胞黏附具有良好的效果，没有致突变或致癌作用。开发的导电复合气凝胶可用作组织工程应用的合适支架，这些应用需要良好的灵活性、尺寸稳定性、热稳定性和生物相容性之间的平衡。
