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在一家多地点三级中心住院的患者中,检出佩滕科夫葡萄球菌阳性血培养。

Staphylococcus pettenkoferi-positive Blood cultures in Hospitalized Patients in a Multi-site Tertiary Center.

机构信息

Division of Infectious Diseases, Detroit Medical Center, Detroit, MI, USA.

Department of Pathology, Wayne State University School of Medicine, Detroit, MI, USA; Microbiology Division, DMC University Laboratories, Detroit Medical Center, Detroit, MI, USA.

出版信息

Diagn Microbiol Infect Dis. 2021 Apr;99(4):115284. doi: 10.1016/j.diagmicrobio.2020.115284. Epub 2020 Dec 5.

Abstract

Staphylococcus pettenkoferi (S.pettenkoferi), originally described in Germany in 2002 by Trülzsch et al, is a coagulase negative staphylococcus whose clinical relevance is yet to be determined. With about 10 case reports in the literature from several parts of the world, there is no data on S. pettenkoferi infection from the United States. This is a retrospective cohort study of 80 patients ≥ 18 years of age who had at least 1 S. pettenkoferi-positive blood culture, identified by matrix-assisted laser desorption/ionization time-of-flight at a tertiary academic center in Detroit, Michigan. We describe the features of S. pettenkoferi-positive blood cultures in order to identify cases of true bacteremia. The mean age of the cohort was 66 ± 16 years and 1 out of 3 had immunosuppressing conditions. No case of true S.pettenkoferi bacteremia was identified. More studies are needed to determine its role as a pathogen in the United States.

摘要

葡萄球菌 pettenkoferi(S.pettenkoferi),最初于 2002 年由 Trülzsch 等人在德国描述,是一种凝固酶阴性葡萄球菌,其临床相关性尚未确定。文献中有来自世界各地的大约 10 例病例报告,但美国没有关于 S. pettenkoferi 感染的数据。这是在密歇根州底特律的一家三级学术中心,通过基质辅助激光解吸/电离飞行时间对 80 名年龄≥18 岁的至少有 1 次 S. pettenkoferi 阳性血培养的患者进行的回顾性队列研究。我们描述了 S. pettenkoferi 阳性血培养的特征,以确定真正菌血症的病例。队列的平均年龄为 66 ± 16 岁,1/3 的患者存在免疫抑制情况。未发现真正的 S.pettenkoferi 菌血症病例。需要更多的研究来确定它在美国作为病原体的作用。

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