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应用热塑无框架面罩和天花板-地板式图像引导装置评估颅内立体定向放射外科中的分次内头部运动。

Evaluation of intrafractional head motion for intracranial stereotactic radiosurgery with a thermoplastic frameless mask and ceiling-floor-mounted image guidance device.

机构信息

Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto 606-8507, Japan; Division of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto 606-8507, Japan.

出版信息

Phys Med. 2021 Jan;81:245-252. doi: 10.1016/j.ejmp.2020.12.019. Epub 2021 Jan 20.

Abstract

PURPOSE

To evaluate intrafractional head motion (IFM) in patients who underwent intracranial stereotactic radiosurgery with the ExacTrac X-ray system (ETX) and a frameless mask.

METHODS

A total of 143 patients who completed a pre-treatment examination for IFM were eligible for this study. The frameless mask type B R408 (Klarity Medical & Equipment Co., Ltd., Guangzhou, China), which covers the back of the head, and the entire face, was used for patient immobilization. After the initial 6D correction and first X-ray verification (IFM), X-ray verification was performed every 3 min for a duration of 15 min. The IFM (2 ≤ p ≤ 6) was calculated as the positional difference from IFM. In addition, the inter-phase IFM (IP-IFM) and IFM were calculated. The IP-IFM was defined as |IFM - IFM|, and IFM as the difference between the values after all patients were asked to move their heads intentionally with the frameless mask on.

RESULTS

Both translational IFM and IP-IFM exceeded 1 mm for a single patient, whereas, for all patients, the translational IFM values were kept to within 1 mm in all directions. The proportions of the rotational IFM, IP-IFM, and IFM values within 0.5° were greater than 94.4%, 98.6%, and 90.2% for all of the rotational axes, respectively.

CONCLUSIONS

A frameless mask achieved highly accurate patient positioning in combination with ETX and a 6°-of-freedom robotic couch; however, a deviation over 1 mm and 0.5° was observed with low frequency. Therefore, X-ray verification and correction are required during treatment.

摘要

目的

评估接受颅内立体定向放射外科治疗的患者的分次内头部运动(IFM),使用 ExacTrac X 射线系统(ETX)和无框架面罩。

方法

本研究共纳入 143 名完成 IFM 预治疗检查的患者。使用无框架面罩型 B R408(广州科立盈医疗设备有限公司)固定患者头部和整个面部。初始 6D 校正和首次 X 射线验证(IFM)后,每 3 分钟进行一次 X 射线验证,持续 15 分钟。IFM(2≤p≤6)的计算方法为 IFM 的位置差异。此外,还计算了相位间 IFM(IP-IFM)和 IFM。IP-IFM 定义为 IFM-IFM,IFM 定义为所有患者在无框架面罩固定下故意移动头部后的差值。

结果

单个患者的平移 IFM 和 IP-IFM 均超过 1mm,但所有患者的平移 IFM 值均保持在 1mm 以内。所有旋转轴的旋转 IFM、IP-IFM 和 IFM 值的比例均大于 94.4%、98.6%和 90.2%。

结论

无框架面罩与 ETX 和 6 自由度机器人床相结合,可实现高精度的患者定位;但观察到 1mm 和 0.5°的偏差频率较低。因此,治疗过程中需要进行 X 射线验证和校正。

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