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单纯孕激素避孕药使用者的人体测量指数、血压和血脂状况:比较横断面研究。

Anthropometric indices, blood pressure, and lipid profile status among women using progestin-only contraceptives: comparative cross-sectional study.

机构信息

Department of Nursing, College of Health Science, Woldia University, 400, Woldia, Ethiopia.

Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arbaminch University, Arba Minch, Ethiopia.

出版信息

BMC Womens Health. 2021 Jan 23;21(1):34. doi: 10.1186/s12905-021-01178-8.

Abstract

BACKGROUND

The major types of hormonal contraception used currently in Ethiopia are progestogen-only. This study aimed to assess the differences in anthropometry indices, blood pressure, and lipid profile among women using progestin-only contraceptives in selected health facilities of Jimma town, southwest Ethiopia.

METHODS

A facility-based comparative cross-sectional study was conducted among women of reproductive age using Depo-medroxyprogesterone acetate (DMPA) and implant in selected health facilities from April 11 to May 11, 2019. A total of 146 women (45 DMPA and 51 implant users and 50 non-users) were selected randomly for inclusion in the study. One-way analysis of variance was used to examine variations in health outcomes while Bonferroni post-hoc tests were conducted to determine significance of variations between multiple outcomes.

RESULTS

There was a statistically significant difference in the mean Body Mass Index (p = 0.045), Hip-to-waist ratio (p = 0.012), systolic blood pressure (p = 0.027), diastolic blood pressure (DBP) (p = 0.017), total cholesterol (TC) (p = 0.005), low-density lipoprotein (p = 0.023) and triacylglycerol (TAG) (p = 0.000) between women using progestin-only contraceptives and non-users. DMPA users had higher TC (p = 0.024) than non-users. Results from Pearson correlation analysis showed that DBP of DMPA users was higher with longer duration of use.

CONCLUSION

The findings suggest the need for family planning service providers to undertake appropriate client profiling before recommending a particular method to women seeking the services in order to minimize adverse health risks, especially for those who may have pre-existing conditions.

摘要

背景

目前埃塞俄比亚使用的主要激素避孕方法是孕激素避孕药。本研究旨在评估在吉姆马镇选定的卫生机构中使用单纯孕激素避孕药的妇女的人体测量指数、血压和血脂谱的差异。

方法

2019 年 4 月 11 日至 5 月 11 日,在使用 Depotmedroxyprogesterone 醋酸酯(DMPA)和植入物的育龄妇女中,在选定的卫生设施中进行了基于设施的比较性横断面研究。共有 146 名妇女(45 名 DMPA 和 51 名植入物使用者和 50 名非使用者)被随机选择纳入研究。使用单向方差分析来检查健康结果的变化,同时进行 Bonferroni 事后检验以确定多个结果之间变化的显著性。

结果

在体重指数(p=0.045)、臀围与腰围比(p=0.012)、收缩压(p=0.027)、舒张压(DBP)(p=0.017)、总胆固醇(TC)(p=0.005)、低密度脂蛋白(p=0.023)和三酰甘油(TAG)(p=0.000)方面,使用单纯孕激素避孕药的妇女与非使用者之间存在统计学显著差异。DMPA 使用者的 TC 较高(p=0.024),而非使用者。Pearson 相关分析结果表明,DMPA 使用者的 DBP 随着使用时间的延长而升高。

结论

这些发现表明,计划生育服务提供者在向寻求服务的妇女推荐特定方法之前,需要对客户进行适当的分析,以尽量减少不良健康风险,特别是对那些可能有潜在疾病的妇女。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c85/7824919/44fd8cc63ae4/12905_2021_1178_Fig1_HTML.jpg

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