[脑脊液中的C反应蛋白、乳酸及乳酸脱氢酶同工酶在儿童脑膜炎诊断中的应用]
[C-reactive protein, lactate and LDH isoenzymes in the cerebrospinal fluid in the diagnosis in childhood meningitis].
作者信息
Castro-Gago M, Couce M L, Losada M C, González M C, Novo I, España M R, Rodríguez-Segade S
机构信息
Departamento de Pediatría, Hospital General de Galicia, Facultad de Medicina, Universidad de Santiago de Compostela.
出版信息
An Esp Pediatr. 1988 Jan;28(1):31-3.
C reactive protein lactate and LDH isoenzymes were quantified in CSF of 32 children with meningitis (27 bacterial and 5 viral). Results in cases with bacterial meningitis were as follows. C reactive protein sensitivity was 11.1% and specificity was 100%. Lactate sensitivity was 33.3% and its specificity was 80%. LDH1 and LDH5 had a sensitivity of 44.4%, and specificities of 100 and 60% respectively. Considering these results an has believe that none of these tests is definitive in diagnosis of bacterial meningitis in children.
对32例脑膜炎患儿（27例细菌性脑膜炎和5例病毒性脑膜炎）的脑脊液进行了C反应蛋白、乳酸和乳酸脱氢酶同工酶定量检测。细菌性脑膜炎病例的检测结果如下：C反应蛋白的敏感性为11.1%，特异性为100%；乳酸的敏感性为33.3%，特异性为80%；乳酸脱氢酶1和乳酸脱氢酶5的敏感性为44.4%，特异性分别为100%和60%。基于这些结果，有人认为这些检测方法均不能确诊儿童细菌性脑膜炎。
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