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无菌性肩骨坏死:病因、诊断与医学治疗。

Aseptic osteonecrosis of the shoulder: Etiologies, diagnosis and medical management.

机构信息

Département de chirurgie osseuse, CHU Angers, 4, rue Larrey, 49933 Angers cedex 9, France.

Département de chirurgie osseuse, CHU Angers, 4, rue Larrey, 49933 Angers cedex 9, France; GEROM - Groupe Etudes Remodelage Osseux et bioMatériaux, IRIS-IBS institut de biologie en santé, université d'Angers, 49933 Angers, France.

出版信息

Morphologie. 2021 Jun;105(349):148-154. doi: 10.1016/j.morpho.2020.12.010. Epub 2021 Jan 21.

Abstract

Aseptic osteonecrosis of the humeral head is a multifactorial entity in which the final common pathway results in disrupted blood supply, increased intraosseous pressure, and bone death. It follows a pathologic and radiographic pattern of progression similar to that seen at the hip. Much of the information regarding the disease has been extrapolated from findings in the femoral head. In addition, many treatment modalities have been adapted from techniques used in the hip. The causative underlying factors seem to be multifactorial and can be traumatic or non-traumatic. Although clinical symptoms and the underlying cause of the disease influence the treatment of each patient, staging is the most objective criterion in determining the most appropriate treatment. Earlier identification of osteonecrosis should facilitate the management. MRI is important for asymptomatic humeral head osteonecrosis in patients with poor clinical symptom and risk factor. Conservative treatment can be effective in stages I and II, When symptoms persist and there are signs of collapse despite conservative treatment, surgical intervention is advocated.

摘要

肱骨头无菌性坏死是一种多因素疾病,其最终共同途径导致血液供应中断、骨内压升高和骨坏死。它遵循与髋关节相似的病理和影像学进展模式。关于这种疾病的大部分信息都是从股骨头的发现中推断出来的。此外,许多治疗方法都是从髋关节的技术中改编而来的。致病的潜在因素似乎是多因素的,可能是创伤性的或非创伤性的。尽管临床症状和疾病的根本原因影响着每位患者的治疗,但分期是确定最合适治疗方法的最客观标准。早期发现骨坏死有助于治疗。对于临床症状和危险因素较差的无症状肱骨头骨坏死患者,MRI 很重要。对于 I 期和 II 期,保守治疗可能有效。当症状持续存在且尽管保守治疗仍有塌陷迹象时,应提倡手术干预。

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