Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Jiangsu, Lianyungang, 222001, China.
Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Jiangsu, Lianyungang, 222001, China.
J Gynecol Obstet Hum Reprod. 2021 Oct;50(8):102071. doi: 10.1016/j.jogoh.2021.102071. Epub 2021 Jan 21.
Intrauterine insemination (IUI) is a first-line treatment for unexplained infertility (UI). There was a compelling need for the improvement of pregnancy rate in females with UI.
To explore the pregnancy predictors in cases of UI undergoing IUI.
A total of 212 couples who underwent 446 IUI cycles were involved the study. Different factors were grouped to explore the influencing factors of IUI for UI.
Female age and somking affected pregnancy outcomes. As the number of treatment cycles increased, the pregnancy rate increased. The BMI, treatment regimens, type of infertility, endometrium, and timing insemination have no significant prognostic value.
Apart from the number of treatment cycles, somking, and female age, no other factors had prognostic value. More studies and samples are necessary to evaluate whether other factors affect conception.
宫腔内人工授精（IUI）是不明原因不孕（UI）的一线治疗方法。迫切需要提高 UI 女性的妊娠率。
探讨 IUI 治疗 UI 的妊娠预测因素。
本研究共纳入 212 对夫妇的 446 个 IUI 周期。将不同因素分组，探讨影响 UI 行 IUI 的因素。
女性年龄和吸烟影响妊娠结局。随着治疗周期数的增加，妊娠率增加。BMI、治疗方案、不孕类型、子宫内膜和授精时机均无显著预后价值。
除了治疗周期数、吸烟和女性年龄外，没有其他因素具有预后价值。需要更多的研究和样本来评估其他因素是否影响受孕。
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