Eating Disorders Center for Treatment and Research, Department of Neuroscience, University of Turin, Via Cherasco 11, 10126, Turin, Italy.
Psychiatry Res. 2021 Mar;297:113734. doi: 10.1016/j.psychres.2021.113734. Epub 2021 Jan 15.
Anorexia Nervosa (AN) and Major Depressive Disorder (MDD) are frequent comorbid conditions. It is unclear how MDD affects intensive emergency treatment and outcome. Eighty-seven AN inpatients were analyzed, twenty-two suffered also from MDD. Individuals with AN and MDD at admission had no remarkable differences in psychopathology, but a full diagnosis of MDD - and not just the presence of depressive symptoms - was associated with longer length of stay and worse clinical outcome (weight restoration, increase of caloric intake). Health care policies might consider that MDD comorbidity, regardless of AN clinical severity, affects the efficacy and timing of acute treatments.
神经性厌食症 (AN) 和重度抑郁症 (MDD) 是常见的共病。目前尚不清楚 MDD 如何影响强化急诊治疗和结果。对 87 名 AN 住院患者进行了分析，其中 22 名患者还患有 MDD。入院时患有 AN 和 MDD 的个体在精神病理学方面没有显著差异，但 MDD 的全面诊断 - 而不仅仅是存在抑郁症状 - 与住院时间延长和临床结局恶化（体重恢复、增加热量摄入）相关。医疗保健政策可能会考虑到，无论 AN 临床严重程度如何，MDD 共病都会影响急性治疗的效果和时机。
