• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

目标性住院医师干预可减少阿片类药物的使用,而不会加重患者报告的疼痛评分,并改善 IBD 患者的结局:“IBD 疼痛阶梯”。

Targeted housestaff intervention reduces opioid use without worsening patient-reported pain scores and improves outcomes among patients with IBD: the "IBD pain ladder".

机构信息

Department of Internal Medicine, University of Illinois Chicago, Chicago, IL, USA.

Division of Gastroenterology and Hepatology, University of Illinois Chicago, Chicago, IL, USA.

出版信息

Int J Colorectal Dis. 2021 Jun;36(6):1193-1200. doi: 10.1007/s00384-021-03852-7. Epub 2021 Jan 23.

DOI:10.1007/s00384-021-03852-7
PMID:33486534
Abstract

BACKGROUND AND AIMS

Opioid analgesic use is associated with increased mortality, higher readmission rates, and reduced quality of life among patients with inflammatory bowel disease (IBD). With the goal of reducing inpatient opioid use among patients with IBD admitted to our inpatient gastroenterology (GI) service, we designed and implemented a standardized, educational intervention providing analgesic decision support to internal medicine and emergency medicine housestaff at our institution.

METHODS

Pre-intervention data was collected from patients admitted during a 9-month period prior to intervention. Post-intervention patients were identified prospectively. The primary outcome was reduction in aggregate inpatient opioid use in oral morphine equivalents per patient.

RESULTS

A total of 68 patients with 81 hospitalizations were analyzed. There was no statistically significant difference in baseline admission characteristics between the two groups. Our primary outcome was achieved with a statistically significant reduction in opioid use during hospitalization (43.4 mg vs 7.7 mg; p < 0.01). Secondary outcomes achieved included reduction in new opioid prescriptions upon discharge, reduced hospital length of stay, and reduced 90-day readmission rates. There was no significant difference between patients' pain scores between the two groups.

CONCLUSION

We believe this intervention, aimed at housestaff education, provides a roadmap for pain management decision-making in this patient population. It is a readily reproducible strategy that can be widely applied to improve inpatient IBD patient care. Importantly, patient experience and pain scores were unchanged despite lower use of inpatient opioid analgesia, highlighting successful opioid-sparing analgesics in most inpatients with IBD.

摘要

背景与目的

阿片类镇痛药的使用与炎症性肠病(IBD)患者的死亡率增加、再入院率升高和生活质量降低有关。为了减少我院住院胃肠病学(GI)服务收治的 IBD 患者的住院阿片类药物使用量,我们设计并实施了一项标准化的教育干预措施,为我们机构的内科和急诊住院医师提供镇痛决策支持。

方法

在干预前的 9 个月期间收集了接受干预前患者的数据。前瞻性地识别了接受干预后的患者。主要结局是减少每位患者的住院口服吗啡等效物的总体阿片类药物使用量。

结果

共分析了 68 例患者的 81 例住院情况。两组患者的基线入院特征无统计学差异。我们的主要结局是在住院期间的阿片类药物使用量显著减少(43.4mg 比 7.7mg;p<0.01)。达到的次要结局包括出院时新的阿片类药物处方减少、住院时间缩短和 90 天再入院率降低。两组患者的疼痛评分无显著差异。

结论

我们认为,针对住院医师教育的这种干预措施为该患者人群的疼痛管理决策提供了指导。这是一种易于复制的策略,可以广泛应用于改善 IBD 住院患者的护理。重要的是,尽管住院阿片类镇痛药使用量减少,但患者的体验和疼痛评分没有改变,这突出了大多数 IBD 住院患者成功使用了阿片类药物节约型镇痛剂。

相似文献

1
Targeted housestaff intervention reduces opioid use without worsening patient-reported pain scores and improves outcomes among patients with IBD: the "IBD pain ladder".目标性住院医师干预可减少阿片类药物的使用,而不会加重患者报告的疼痛评分,并改善 IBD 患者的结局:“IBD 疼痛阶梯”。
Int J Colorectal Dis. 2021 Jun;36(6):1193-1200. doi: 10.1007/s00384-021-03852-7. Epub 2021 Jan 23.
2
P041 Successful Reduction in Opioid Prescription for IBD Flare in the Emergency Department: A Retrospective Study and Quality Improvement Initiative.P041 急诊科成功减少炎症性肠病发作时的阿片类药物处方:一项回顾性研究及质量改进计划
Am J Gastroenterol. 2021 Dec 1;116(Suppl 1):S10-S11. doi: 10.14309/01.ajg.0000798764.14625.6a.
3
A randomized controlled trial of a proactive analgesic protocol demonstrates reduced opioid use among hospitalized adults with inflammatory bowel disease.一项主动镇痛方案的随机对照试验表明,炎性肠病住院成人的阿片类药物使用量减少。
Sci Rep. 2023 Dec 16;13(1):22396. doi: 10.1038/s41598-023-48126-0.
4
A Multimodal Intervention Using Nonopioid Analgesics Is Associated With Reduced Intravenous Opioid Exposure Among Hospitalized Patients With Inflammatory Bowel Diseases.一项使用非阿片类镇痛药的多模式干预与住院炎症性肠病患者静脉阿片类药物暴露减少相关。
Am J Gastroenterol. 2020 Sep;115(9):1474-1485. doi: 10.14309/ajg.0000000000000806.
5
Pain in Inflammatory Bowel Disease Is Not Improved During Hospitalization: The Impact of Opioids on Pain and Healthcare Utilization.炎症性肠病的疼痛在住院期间并未得到改善:阿片类药物对疼痛和医疗保健利用的影响。
Dig Dis Sci. 2020 Jun;65(6):1777-1783. doi: 10.1007/s10620-019-05906-x. Epub 2019 Oct 25.
6
Effect of a preoperative gabapentin on postoperative analgesia in patients with inflammatory bowel disease following major bowel surgery: a randomized, placebo-controlled trial.术前加巴喷丁对炎症性肠病患者大肠道手术后术后镇痛的影响:一项随机、安慰剂对照试验。
Pain Pract. 2014 Feb;14(2):132-9. doi: 10.1111/papr.12058. Epub 2013 Apr 8.
7
A Novel Opioid-Sparing Pain Management Protocol Following Total Hip Arthroplasty: Effects on Opioid Consumption, Pain Severity, and Patient-Reported Outcomes.一种新型的全髋关节置换术后阿片类药物节约型疼痛管理方案:对阿片类药物消耗、疼痛严重程度和患者报告结果的影响。
J Arthroplasty. 2019 Nov;34(11):2669-2675. doi: 10.1016/j.arth.2019.06.038. Epub 2019 Jun 26.
8
A Multi-institutional Assessment of Multimodal Analgesia in Penile Implant Recipients Demonstrates Dramatic Reduction in Pain Scores and Narcotic Usage.多模式镇痛在阴茎植入患者中的多机构评估显示疼痛评分和麻醉药物使用量显著降低。
J Sex Med. 2020 Mar;17(3):518-525. doi: 10.1016/j.jsxm.2019.11.267. Epub 2019 Dec 20.
9
Preadmission Cannabis Use Is Positively Correlated With Inpatient Opioid Dose Exposure in Hospitalized Patients With Inflammatory Bowel Diseases.住院炎症性肠病患者入院前大麻使用与住院期间阿片类药物剂量暴露呈正相关。
Inflamm Bowel Dis. 2021 Mar 15;27(4):500-506. doi: 10.1093/ibd/izaa104.
10
A retrospective comparison of thoracic epidural infusion and multimodal analgesia protocol for pain management following the minimally invasive repair of pectus excavatum.鸡胸微创修复术后疼痛管理中胸段硬膜外输注与多模式镇痛方案的回顾性比较。
Paediatr Anaesth. 2017 Dec;27(12):1227-1234. doi: 10.1111/pan.13264. Epub 2017 Oct 24.

引用本文的文献

1
Chronic Abdominal Pain in Patients with Inflammatory Bowel Disease in Remission: A Continuing Challenge for Clinicians.缓解期炎症性肠病患者的慢性腹痛:临床医生面临的持续挑战。
Dig Dis Sci. 2024 Dec;69(12):4336-4346. doi: 10.1007/s10620-024-08716-y. Epub 2024 Nov 13.
2
Quality improvement exercises in Inflammatory Bowel Disease (IBD) services: A scoping review.炎症性肠病(IBD)服务中的质量改进措施:范围综述。
PLoS One. 2024 Mar 7;19(3):e0298374. doi: 10.1371/journal.pone.0298374. eCollection 2024.
3
Chronic abdominal pain in inflammatory bowel disease: a practical guide.
炎症性肠病中的慢性腹痛:实用指南
Frontline Gastroenterol. 2023 Oct 11;15(2):144-153. doi: 10.1136/flgastro-2023-102471. eCollection 2024.