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采用常规睾丸精子提取术为患有津纳综合征的患者获取精子以进行辅助生殖。

Sperm retrieval by conventional testicular sperm extraction for assisted reproduction in patients with Zinner syndrome.

作者信息

Cito Gianmartin, Gemma Luca, Giachini Claudia, Micelli Elisabetta, Cocci Andrea, Fucci Rossella, Picone Rita, Sforza Simone, Nesi Gabriella, Santi Raffaella, Minervini Andrea, Masieri Lorenzo, Carini Marco, Coccia Maria Elisabetta, Natali Alessandro

机构信息

Department of Urology, Careggi Hospital, Florence, Italy.

Assisted Reproductive Technology Centre, Careggi Hospital, Florence, Italy.

出版信息

Clin Exp Reprod Med. 2021 Mar;48(1):85-90. doi: 10.5653/cerm.2020.03769. Epub 2021 Jan 25.

DOI:10.5653/cerm.2020.03769
PMID:33486943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7943355/
Abstract

We present data from three Caucasian men with Zinner syndrome who attended our center for the treatment of primary couple's infertility. Each patient was scheduled for conventional testicular sperm extraction (cTESE) and cryopreservation. Sperm analysis confirmed absolute azoospermia. Patient 1 had right and left testis volumes of 24 mL and 23 mL, respectively; left seminal vesicle (SV) agenesis, severe right SV hypotrophy with right renal agenesis. Follicle-stimulating hormone (FSH) was 3.2 IU/L. Patient 2 exhibited right and left testis volumes of 18 mL and 16 mL, respectively; a left SV cyst of 32 × 28 mm, ipsilateral kidney absence, and right SV agenesis. FSH was 2.8 IU/L. Patient 3 showed a testicular volume of 10 mL bilaterally, a 65 × 46 mm left SV cyst, right SV enlargement, and left kidney agenesis. FSH was 32.0 IU/L. Sperm retrieval was successful in all patients. Nevertheless, cTESE should be performed on the day of oocyte retrieval.

摘要

我们展示了三名患有津纳综合征的白种男性的数据,他们因原发性夫妻不育前来我们中心接受治疗。每位患者都计划进行常规睾丸精子提取(cTESE)和冷冻保存。精液分析证实为绝对无精子症。患者1的右侧和左侧睾丸体积分别为24 mL和23 mL;左侧精囊(SV)缺如,右侧严重SV发育不良伴右肾缺如。促卵泡激素(FSH)为3.2 IU/L。患者2的右侧和左侧睾丸体积分别为18 mL和16 mL;左侧SV囊肿大小为32×28 mm,同侧肾缺如,右侧SV缺如。FSH为2.8 IU/L。患者3双侧睾丸体积均为10 mL,左侧SV囊肿大小为65×46 mm,右侧SV增大,左侧肾缺如。FSH为32.0 IU/L。所有患者的精子采集均成功。尽管如此,cTESE应在取卵当天进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/8a2c5397ae5a/cerm-2020-03769f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/84fb19976635/cerm-2020-03769f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/43af58b82e8e/cerm-2020-03769f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/8a2c5397ae5a/cerm-2020-03769f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/84fb19976635/cerm-2020-03769f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/43af58b82e8e/cerm-2020-03769f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363d/7943355/8a2c5397ae5a/cerm-2020-03769f3.jpg

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2
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Andrologia. 2020 Feb;52(1):e13397. doi: 10.1111/and.13397. Epub 2019 Nov 15.
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