Kesavan Rajesh, Purushothaman Shyam Sundar, Tosh Pulak, Balakrishnan Sindhu, Varghese Rekha, Rajan Sunil
Department of Anaesthesiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Anesth Essays Res. 2020 Apr-Jun;14(2):331-334. doi: 10.4103/aer.AER_74_20. Epub 2020 Oct 12.
Awake patients complain of burning sensation following nasal application of lignocaine jelly.
The aim of the study was to assess hemodynamic changes, ease of insertion, number of attempts taken, and time required for insertion of Ryle's tube following nasal application of 2% lignocaine jelly versus lubricant gel in patients undergoing surgeries under general anesthesia.
This was a prospective, randomized, open-label study conducted in a tertiary care institute.
Eighty patients undergoing surgeries under general anesthesia who required insertion of a Ryle's tube were included. In Group A, 2% lignocaine jelly was used, whereas in Group B, lubricant gel was used prior to Ryle's tube insertion, after induction of anesthesia. Hypertension and/or tachycardia were managed by increasing sevoflurane by 0.5%-1%, followed by propofol bolus of 0.5 mg.kg.
Chi-square test and Independent samples t test.
Both heart rate and mean arterial pressure were significantly higher at 1 min after nasal application of lignocaine jelly and 1 and 5 min after Ryle's tube insertion in Group A compared to Group B. Ease of insertion of Ryle's tube, number of attempts, and time taken for insertion were comparable in both groups. Significantly higher number of patients in Group A required sevoflurane to be increased and needed propofol boluses.
Use of lubricant gel for aiding insertion of Ryle's tube in patients under general anesthesia was associated with attenuated heart rate and blood pressure responses without affecting the ease, number of attempts, or time taken for successful insertion of the Ryle's tube.
清醒患者在鼻腔应用利多卡因凝胶后会抱怨有烧灼感。
本研究的目的是评估在全身麻醉下接受手术的患者中,鼻腔应用2%利多卡因凝胶与润滑剂凝胶后,留置胃管时的血流动力学变化、插入的难易程度、尝试次数以及插入所需时间。
这是一项在三级医疗机构进行的前瞻性、随机、开放标签研究。
纳入80例在全身麻醉下接受手术且需要留置胃管的患者。A组使用2%利多卡因凝胶,而B组在麻醉诱导后留置胃管前使用润滑剂凝胶。通过将七氟醚增加0.5%-1%,随后推注0.5mg/kg丙泊酚来处理高血压和/或心动过速。
卡方检验和独立样本t检验。
与B组相比,A组在鼻腔应用利多卡因凝胶后1分钟以及留置胃管后1分钟和5分钟时,心率和平均动脉压均显著更高。两组在留置胃管的插入难易程度、尝试次数和插入时间方面相当。A组中需要增加七氟醚并需要推注丙泊酚的患者数量显著更多。
在全身麻醉患者中使用润滑剂凝胶辅助留置胃管与心率和血压反应减弱相关,且不影响胃管成功插入的难易程度、尝试次数或所需时间。