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利多卡因凝胶与润滑凝胶经鼻应用的血流动力学变化比较以及在全身麻醉患者中使用后对留置胃管的反应

Comparison of Hemodynamic Changes to Nasal Application of Lignocaine Jelly versus Lubricant Gel and Responses to Ryle's Tube Insertion Following Their Use in Patients Under General Anesthesia.

作者信息

Kesavan Rajesh, Purushothaman Shyam Sundar, Tosh Pulak, Balakrishnan Sindhu, Varghese Rekha, Rajan Sunil

机构信息

Department of Anaesthesiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

出版信息

Anesth Essays Res. 2020 Apr-Jun;14(2):331-334. doi: 10.4103/aer.AER_74_20. Epub 2020 Oct 12.

Abstract

BACKGROUND

Awake patients complain of burning sensation following nasal application of lignocaine jelly.

AIM OF THE STUDY

The aim of the study was to assess hemodynamic changes, ease of insertion, number of attempts taken, and time required for insertion of Ryle's tube following nasal application of 2% lignocaine jelly versus lubricant gel in patients undergoing surgeries under general anesthesia.

SETTINGS AND DESIGN

This was a prospective, randomized, open-label study conducted in a tertiary care institute.

SUBJECTS AND METHODS

Eighty patients undergoing surgeries under general anesthesia who required insertion of a Ryle's tube were included. In Group A, 2% lignocaine jelly was used, whereas in Group B, lubricant gel was used prior to Ryle's tube insertion, after induction of anesthesia. Hypertension and/or tachycardia were managed by increasing sevoflurane by 0.5%-1%, followed by propofol bolus of 0.5 mg.kg.

STATISTICAL TESTS USED

Chi-square test and Independent samples t test.

RESULTS

Both heart rate and mean arterial pressure were significantly higher at 1 min after nasal application of lignocaine jelly and 1 and 5 min after Ryle's tube insertion in Group A compared to Group B. Ease of insertion of Ryle's tube, number of attempts, and time taken for insertion were comparable in both groups. Significantly higher number of patients in Group A required sevoflurane to be increased and needed propofol boluses.

CONCLUSION

Use of lubricant gel for aiding insertion of Ryle's tube in patients under general anesthesia was associated with attenuated heart rate and blood pressure responses without affecting the ease, number of attempts, or time taken for successful insertion of the Ryle's tube.

摘要

背景

清醒患者在鼻腔应用利多卡因凝胶后会抱怨有烧灼感。

研究目的

本研究的目的是评估在全身麻醉下接受手术的患者中,鼻腔应用2%利多卡因凝胶与润滑剂凝胶后,留置胃管时的血流动力学变化、插入的难易程度、尝试次数以及插入所需时间。

设置与设计

这是一项在三级医疗机构进行的前瞻性、随机、开放标签研究。

研究对象与方法

纳入80例在全身麻醉下接受手术且需要留置胃管的患者。A组使用2%利多卡因凝胶,而B组在麻醉诱导后留置胃管前使用润滑剂凝胶。通过将七氟醚增加0.5%-1%,随后推注0.5mg/kg丙泊酚来处理高血压和/或心动过速。

所用统计检验

卡方检验和独立样本t检验。

结果

与B组相比,A组在鼻腔应用利多卡因凝胶后1分钟以及留置胃管后1分钟和5分钟时,心率和平均动脉压均显著更高。两组在留置胃管的插入难易程度、尝试次数和插入时间方面相当。A组中需要增加七氟醚并需要推注丙泊酚的患者数量显著更多。

结论

在全身麻醉患者中使用润滑剂凝胶辅助留置胃管与心率和血压反应减弱相关,且不影响胃管成功插入的难易程度、尝试次数或所需时间。

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本文引用的文献

2
Lidocaine gel as an anesthetic protocol for nasogastric tube insertion in the ED.
Am J Emerg Med. 2011 May;29(4):386-90. doi: 10.1016/j.ajem.2009.10.011. Epub 2010 Mar 25.
4
Neuroendocrine stress response and heart rate variability: a comparison of total intravenous versus balanced anesthesia.
Anesth Analg. 2005 Dec;101(6):1700-1705. doi: 10.1213/01.ane.0000184041.32175.14.
7
Hemodynamic responses among three tracheal intubation devices in normotensive and hypertensive patients.
Anesth Analg. 2003 Mar;96(3):890-895. doi: 10.1213/01.ANE.0000048706.15720.C9.
9
The role of epidural anesthesia and analgesia in postoperative outcome.
Anesthesiol Clin North Am. 2000 Jun;18(2):407-28, viii. doi: 10.1016/s0889-8537(05)70170-x.
10
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Anesthesiology. 2000 Jul;93(1):141-7. doi: 10.1097/00000542-200007000-00024.

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