Sankar J, Majumdar S S, Unniyal Manish, Singh Harmanpreet, Khullar Atul, Kumar Kishore
Graded Specialist (Medicine), Military Hospital Chennai, Tamilnadu, India.
Classified Specialist (Radiodiagnosis), Military Hospital Chennai, Tamilnadu, India.
Med J Armed Forces India. 2021 Jan;77(1):96-100. doi: 10.1016/j.mjafi.2018.12.014. Epub 2019 Apr 2.
Central nervous system tuberculoma can have different clinical manifestations like headache, seizures, papilledema or other signs of raised intracranial pressure depending up on the site and number of tuberculoma. We report a case of 56 year old female reported with history of bilateral asymmetric ptosis of one month duration,with no other neurological defecit. Magnetic resonance imaging (MRI) brain revealed well defined ring enhancing lesion in the medial aspect of left hemi midbrain with diffuse disproportionate perilessional edema. Contrast Enhanced Computed Tomogram (CECT) of chest and abdomen revealed features of disseminated tuberculosis. She was diagnosed as a case of disseminated tuberculosis and started on antitubercular therapy with steroids and the ptosis almost resolved after 01 month of antitubercular therapy. Our case report is unique in the sense that only few cases of midbrain tuberculoma causing occulomotor abnormalities are reported in literature.
中枢神经系统结核瘤可因结核瘤的部位和数量不同而有不同的临床表现,如头痛、癫痫发作、视乳头水肿或其他颅内压升高的体征。我们报告一例56岁女性,有持续一个月的双侧不对称上睑下垂病史,无其他神经功能缺损。脑部磁共振成像(MRI)显示左中脑内侧有边界清晰的环形强化病变,伴有弥漫性不成比例的瘤周水肿。胸部和腹部增强计算机断层扫描(CECT)显示播散性结核的特征。她被诊断为播散性结核,并开始接受抗结核治疗及使用类固醇,抗结核治疗1个月后上睑下垂几乎消失。我们的病例报告很独特,因为文献中仅报道了少数引起动眼神经异常的中脑结核瘤病例。