Jindal Seema, Sidhu Gurkaran Kaur, Baryha Gurpreet Kaur, Singh Baltej, Kumari Samiksha, Mahajan Rupali
Department of Anaesthesia and Intensive Care, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.
Department of Anaesthesia and Intensive Care Fortis Hospital, Mohali, Punjab, India.
J Anaesthesiol Clin Pharmacol. 2020 Jul-Sep;36(3):371-376. doi: 10.4103/joacp.JOACP_148_19. Epub 2020 Sep 26.
Sensory afferent nerve branches of lower six thoracic and upper lumbar nerves innervate the anterior abdominal wall and are the therapeutic focus of local anesthetics to provide analgesia for the abdominal surgical incision. Central neuraxial and regional analgesia can provide better control of pain due to right subcostal incision used in open cholecystectomy and attenuate the need for opioids. The earlier studies which showed the benefit of the thoracic paravertebral block (TPVB) for analgesia after upper abdominal surgeries did not compare TPVB with oblique subcostal transversus abdominis plane (OSTAP) block. Therefore, the current study compares the analgesic efficacy of TPVB and OSTAP block in open cholecystectomy.
Seventy consenting adults scheduled for open cholecystectomy were allocated to one of the two groups: ultrasound-guided TPVB (Group I) and ultrasound-guided OSTAP block (Group II). The primary objective of this study is to assess and compare tramadol consumption in 48 h in both the groups along with VAS in post anesthesia care unit, and then at 2, 4, 6, 8, 12, 24, and 48 h. The secondary objective of the study is to assess the incidence of PONV.
The number of doses of rescue analgesia required was less in Group I when compared with Group II ( < 0.001). Patients in Group I had significantly lower pain scores than Group II. Although in the initial 8 h, both groups had comparable pain scores, after 8 h, these scores were significantly lower in patients in Group I. Less postoperative nausea and vomiting was seen in Group I patients (11.7%) in comparison to Group II (18.1%).
Ultrasound-guided TPVB is superior to OSTAP block because of its association with decreased postoperative opioid consumption, lower VAS score, and reduction in opioid-related side effects. Thus, it should be strongly considered as a part of multimodal analgesia regimen in upper abdominal surgeries.
下6个胸神经和上腰神经的感觉传入神经分支支配前腹壁,是局部麻醉药为腹部手术切口提供镇痛的治疗重点。椎管内和区域镇痛可以更好地控制开腹胆囊切除术中右肋下切口所致疼痛,并减少阿片类药物的使用需求。早期研究显示胸段椎旁阻滞(TPVB)对上腹部手术后镇痛有益,但未将TPVB与斜肋下腹横肌平面(OSTAP)阻滞进行比较。因此,本研究比较了TPVB和OSTAP阻滞在开腹胆囊切除术中的镇痛效果。
70例同意接受开腹胆囊切除术的成年患者被分为两组:超声引导下TPVB组(I组)和超声引导下OSTAP阻滞组(II组)。本研究的主要目的是评估和比较两组患者术后48小时内曲马多的消耗量以及麻醉后恢复室的视觉模拟评分(VAS),随后在术后2、4、6、8、12、24和48小时进行评估。本研究的次要目的是评估术后恶心呕吐(PONV)的发生率。
与II组相比,I组所需的补救性镇痛剂量较少(<0.001)。I组患者的疼痛评分明显低于II组。虽然在最初8小时内,两组的疼痛评分相当,但8小时后,I组患者的疼痛评分显著降低。I组患者术后恶心呕吐的发生率(11.7%)低于II组(18.1%)。
超声引导下TPVB优于OSTAP阻滞,因为它与术后阿片类药物消耗量减少、VAS评分降低以及阿片类药物相关副作用减少有关。因此,应强烈考虑将其作为上腹部手术多模式镇痛方案的一部分。