Zhang Ying, Cui Chunying, Wang Lie, Yu Xiaosong, Wang Yu, Wang Xiaoxi
Department of Social Medicine, School of Public Health, China Medical University, Shenyang, Liaoning, People's Republic of China.
Department of General Practice, The First Affiliated Hospital, China Medical University, Shenyang, Liaoning, People's Republic of China.
Cancer Manag Res. 2021 Jan 14;13:393-401. doi: 10.2147/CMAR.S281886. eCollection 2021.
Cancer diagnosis and treatment are long-term traumatic stressors. Depression and anxiety are known to be prevalent in patients with cancer, but post-traumatic disorder (PTSD) has been overlooked frequently in this population. This study aimed to estimate the prevalence of PTSD and examined the mediating role of hope in the relationship between perceived stress and PTSD symptoms in Chinese patients with oral cancer.
A total of 230 oral cancer patients were recruited to complete a questionnaire including the Posttraumatic Stress Checklist-Civilian Version (PCL-C), the Perceived Stress Scale-10 (PSS-10) and the Herth Hope Index (HHI). Analysis of variances (ANOVA)/-test, Person's r and hierarchical linear regression analysis methods were conducted to assess the associations among perceived stress, hope and PTSD symptoms. Asymptotic and resampling strategies were used to explore the mediating role of hope.
The prevalence of PTSD symptoms was 6.05% in Chinese patients with oral cancer. Perceived stress was positively related to PTSD symptoms, explaining 39.9% of the variance. In addition, hope was negatively related to PTSD symptoms, explaining 5.9% of the variance. Besides, the proportion of mediation of hope was 30.06%.
Perceived stress was positively associated with PTSD symptoms, and hope was negatively associated with PTSD symptoms. Furthermore, hope played partial mediating role in the relationship between perceived stress and PTSD symptoms. Thus, more attention should be paid to patients' PTSD status, and take measures is to relieve stress and increase hope.
癌症诊断和治疗是长期的创伤性应激源。众所周知，抑郁症和焦虑症在癌症患者中很普遍，但创伤后应激障碍（PTSD）在这一人群中经常被忽视。本研究旨在评估中国口腔癌患者中创伤后应激障碍的患病率，并检验希望在感知压力与创伤后应激障碍症状之间关系中的中介作用。
共招募了230名口腔癌患者，完成一份问卷，包括创伤后应激检查表 - 平民版（PCL - C）、感知压力量表 - 10（PSS - 10）和赫思希望指数（HHI）。采用方差分析（ANOVA）/ t检验、Person相关系数r和分层线性回归分析方法来评估感知压力、希望和创伤后应激障碍症状之间的关联。采用渐近和重采样策略来探索希望的中介作用。
中国口腔癌患者中创伤后应激障碍症状的患病率为6.05%。感知压力与创伤后应激障碍症状呈正相关，解释了39.9%的变异。此外，希望与创伤后应激障碍症状呈负相关，解释了5.9%的变异。此外，希望的中介比例为30.06%。
感知压力与创伤后应激障碍症状呈正相关，希望与创伤后应激障碍症状呈负相关。此外，希望在感知压力与创伤后应激障碍症状之间的关系中起部分中介作用。因此，应更加关注患者的创伤后应激障碍状况，并采取措施减轻压力和增强希望。
