在巴西亚马逊西部的前流行区玛瑙斯实现淋巴丝虫病传播阻断。
Interruption of lymphatic filariasis transmission in Manaus, a former focus of in the Western Brazilian Amazon.
作者信息
Martins Marilaine, Guimarães Rebeca Cristina Souza, Fontes Gilberto
机构信息
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado Manaus Brazil Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.
Instituto Leônidas e Maria Deane/Fiocruz Amazônia Manaus Brazil Instituto Leônidas e Maria Deane/Fiocruz Amazônia, Manaus, Brazil.
出版信息
Rev Panam Salud Publica. 2021 Jan 15;45:e1. doi: 10.26633/RPSP.2021.1. eCollection 2021.
OBJECTIVE
To confirm the absence of autochthonous cases in Manaus, a former focus of lymphatic filariasis in the Western Brazilian Amazon.
METHODS
A field survey was carried out in 2016 using immunochromatographic rapid tests (ICT card) for the detection of circulating filarial antigens in blood. The sample included a group of 3 000 schoolchildren aged 6 to 10 years enrolled in schools from different urban areas of Manaus (including the former lymphatic filariasis focus in the city) and a group of 709 adolescents and adults, between the ages of 11 and 85 years, born and raised in different areas of Manaus.
RESULTS
All of the individuals tested negative for antigen.
CONCLUSIONS
Although Manaus was once considered endemic, this focus no longer seems to be active for lymphatic filariasis transmission. The results of this study could support the certification by the World Health Organization of the lymphatic filariasis transmission elimination exercise in Brazil.
目的
确认巴西亚马孙地区西部曾经的淋巴丝虫病疫源地玛瑙斯不存在本地病例。
方法
2016年开展了一项实地调查，采用免疫层析快速检测（ICT卡）法检测血液中循环丝虫抗原。样本包括一组3000名6至10岁的学童，他们就读于玛瑙斯不同市区的学校（包括该市曾经的淋巴丝虫病疫源地），以及一组709名青少年和成年人，年龄在11至85岁之间，在玛瑙斯不同地区出生并长大。
结果
所有检测个体的抗原检测均为阴性。
结论
尽管玛瑙斯曾被视为疫区，但该疫源地目前似乎已不再有淋巴丝虫病传播活动。本研究结果可为世界卫生组织认证巴西消除淋巴丝虫病传播工作提供支持。
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