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天然淋巴细胞在特定疾病状态——癌症形成、代谢紊乱和炎症中的作用。

The role of innate lymphoid cells in selected disease states - cancer formation, metabolic disorder and inflammation.

作者信息

Poniewierska-Baran Agata, Tokarz-Deptuła Beata, Deptuła Wiesław

机构信息

Department of Immunology, Faculty of Biology, University of Szczecin, Szczecin, Poland.

Veterinary Center of the Nicolaus Copernicus University, Torun, Poland.

出版信息

Arch Med Sci. 2019 Nov 18;17(1):196-206. doi: 10.5114/aoms.2019.89835. eCollection 2021.

Abstract

Innate lymphoid cells (ILCs) are a recently described group of immune cells that can regulate homeostasis and protect mammalian organisms, including humans, from infections and diseases. Considering this, ILC research is still ongoing to better understand the biology of these cells and their roles in the human body. ILCs are a multifunctional group of immune cells, making it important for the medical community to be familiar with the latest research about the ILC families and their functions in selected disease states, such as cancer formation, metabolic disorders and inflammation. By discovering the roles of ILC populations and their participation in many disorders, we can improve disease diagnostics and patient healthcare.

摘要

固有淋巴细胞(ILCs)是最近被描述的一类免疫细胞,它们能够调节体内平衡,并保护包括人类在内的哺乳动物机体免受感染和疾病侵害。鉴于此,关于ILCs的研究仍在继续,以便更好地了解这些细胞的生物学特性及其在人体中的作用。ILCs是一类多功能免疫细胞,因此对于医学界来说,熟悉有关ILC家族及其在特定疾病状态(如癌症形成、代谢紊乱和炎症)中的功能的最新研究非常重要。通过发现ILC群体的作用及其在多种疾病中的参与情况,我们可以改善疾病诊断和患者医疗保健。

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