Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.
Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 171 77 Stockholm, Sweden.
Immunity. 2017 Mar 21;46(3):344-346. doi: 10.1016/j.immuni.2017.03.002.
The development of human innate lymphoid cells (ILCs) remains poorly characterized. In a recent issue of Cell, Lim et al. show that human peripheral-blood CD117 ILCs harbor ILC precursors (ILCPs) derived from hematopoietic stem cells. Peripheral-blood ILCPs can generate all ILC subsets in vivo and in vitro.
人类先天淋巴细胞(ILCs)的发育仍未被充分描述。在最近的一期《Cell》杂志上,Lim 等人表明,人外周血 CD117 ILC 中存在源自造血干细胞的 ILC 前体(ILCP)。外周血 ILCP 可在体内和体外产生所有 ILC 亚群。