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胸腺血管脂肪瘤:重症肌无力患者中一种罕见的胸腺脂肪瘤组织学变异型。

Thymoangiolipoma: A rare histologic variant of thymolipoma in a patient with myasthenia gravis.

作者信息

Anbardar Mohammad Hossein, Amirmoezi Fatemeh, Amirian Armin

机构信息

Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.

Student Research Committee, Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Rare Tumors. 2020 Dec 24;12:2036361320979215. doi: 10.1177/2036361320979215. eCollection 2020.

Abstract

Thymoangiolipoma is a rare, slow-growing, benign thymic neoplasm that arises from the anterior mediastinum. A 61-year-old man with the chief complaint of right eye ptosis and high serum acetylcholine receptor antibody level is presented here. The spiral computed tomography of the chest revealed a hypodense mass in the anterior mediastinum. Microscopic examination showed admixture of adipose tissue, thymic tissue and blood vessels with the diagnosis of thymoangiolipoma. Thymoangiolipoma is a rare histologic variant of thymolipoma which can be associated with myasthenia gravis and must be considered as a differential diagnosis in anterior mediastinal mass with fat density in radiologic evaluation.

摘要

胸腺血管脂肪瘤是一种罕见的、生长缓慢的良性胸腺肿瘤,起源于前纵隔。本文报道了一名61岁男性,主要症状为右眼上睑下垂且血清乙酰胆碱受体抗体水平升高。胸部螺旋计算机断层扫描显示前纵隔有一个低密度肿块。显微镜检查显示脂肪组织、胸腺组织和血管混合存在,诊断为胸腺血管脂肪瘤。胸腺血管脂肪瘤是胸腺脂肪瘤的一种罕见组织学变体,可与重症肌无力相关,在影像学评估中,对于前纵隔脂肪密度肿块必须将其视为鉴别诊断之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed25/7768564/11860c0f977e/10.1177_2036361320979215-fig1.jpg

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