Malek Bouhani, Saida Sakhri, Olfa Jaidane, Salma Kammoun, Maher Slimene, Riadh Chargui, Khaled Rahal
Department of Oncologic Surgery, Salah Azaiz Institute, Tunis, Tunisia.
Université de Tunis El Manar, Faculté de Médecine de Tunis, Tunis, Tunisia.
Rare Tumors. 2020 Dec 27;12:2036361320983691. doi: 10.1177/2036361320983691. eCollection 2020.
Pancreatic metastases are rare, accounting for 2%-3% of pancreatic tumors. The pancreas represents an unusual metastatic site of synovial sarcoma (SS) outside the usual localizations (regional nodes, lung, bone, and liver). The diagnosis is evoked by the personnel medical history of SS and imaging then confirmed by histological examination of the guided pancreatic biopsy. Its therapeutic management is mainly surgical with extensive removal of the lesion. So far only four cases have been reported in the English literature. We reported the case of a male aged 30-year-old who was admitted to our Institute for a local recurrence of SS of the left thigh which was initially treated by surgical excision. The patient underwent a wide surgical excision followed by chemotherapy and radiotherapy. About 15 months later, he experienced a pancreatic metastasis of his SS. He had a caudal splenopancreatectomy with partial resection of the transverse colon followed by chemotherapy. This report highlights the diagnostic difficulties of this rare localization and therapeutic challenge.
胰腺转移瘤较为罕见，占胰腺肿瘤的2%-3%。胰腺是滑膜肉瘤（SS）在常见转移部位（区域淋巴结、肺、骨和肝）之外的一个不寻常的转移部位。诊断通过SS的个人病史及影像学检查提示，随后经胰腺穿刺活检的组织学检查得以证实。其治疗主要是手术切除病变组织。迄今为止，英文文献中仅报道了4例。我们报告了一名30岁男性病例，他因左大腿SS局部复发入住我院，最初接受了手术切除治疗。患者接受了广泛的手术切除，随后进行化疗和放疗。约15个月后，他出现了SS的胰腺转移。他接受了胰尾脾切除术及横结肠部分切除术，随后进行了化疗。本报告强调了这种罕见转移部位的诊断困难及治疗挑战。
